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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPE
All Species:
28.18
Human Site:
Y60
Identified Species:
47.69
UniProt:
O14579
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14579
NP_009194.2
308
34482
Y60
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
F
G
Chimpanzee
Pan troglodytes
XP_001137184
331
36905
Y60
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
F
G
Rhesus Macaque
Macaca mulatta
XP_001114807
308
34452
Y60
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
F
G
Dog
Lupus familis
XP_852205
308
34510
Y60
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
O89079
308
34549
Y60
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
Y
G
Rat
Rattus norvegicus
NP_001099546
166
18646
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515042
306
34392
Y58
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
Y
G
Chicken
Gallus gallus
Q5ZIK9
308
34350
Y60
D
V
F
L
F
R
S
Y
I
A
Q
R
K
Y
G
Frog
Xenopus laevis
NP_001085327
299
33968
P66
V
V
L
D
E
I
R
P
N
A
N
P
E
L
Q
Zebra Danio
Brachydanio rerio
NP_001007365
300
34014
Y58
A
Y
I
A
Q
R
K
Y
G
V
V
L
D
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393328
300
34733
F59
A
Y
I
A
Q
R
K
F
R
V
V
L
D
E
I
Nematode Worm
Caenorhab. elegans
O62246
292
32785
P60
F
I
P
L
K
E
I
P
A
A
T
K
S
A
D
Sea Urchin
Strong. purpuratus
XP_787154
291
33045
Y58
A
Y
A
A
A
G
R
Y
G
V
V
L
D
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64748
293
32640
Q58
Y
I
A
L
G
S
Y
Q
L
V
I
S
E
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
99
94.1
N.A.
90.5
49.6
N.A.
82.4
78.9
77.2
76.6
N.A.
N.A.
62.3
36
49
Protein Similarity:
100
92.7
99.6
97.4
N.A.
95.4
51.2
N.A.
91.5
91.8
90.2
89.6
N.A.
N.A.
77.9
59.4
66.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
93.3
73.3
13.3
13.3
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
100
20
13.3
N.A.
N.A.
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
15
22
8
0
43
0
8
65
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
8
0
0
0
0
0
0
0
0
22
8
15
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
0
0
15
15
0
% E
% Phe:
8
0
50
0
8
0
0
8
0
0
0
0
0
22
0
% F
% Gly:
0
0
0
0
8
8
0
0
15
0
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
15
0
0
8
8
0
8
0
8
0
0
8
15
% I
% Lys:
0
0
0
0
8
0
15
0
0
0
0
8
50
0
0
% K
% Leu:
0
0
8
65
0
0
0
0
50
0
0
22
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
15
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
8
0
0
50
0
0
0
8
% Q
% Arg:
0
0
0
0
0
65
15
0
8
0
0
50
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
0
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
58
0
0
0
0
0
0
0
29
22
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
22
0
0
43
0
8
65
0
0
0
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _