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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFXANK
All Species:
14.85
Human Site:
T218
Identified Species:
46.67
UniProt:
O14593
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14593
NP_003712.1
260
28102
T218
A
R
G
A
D
L
T
T
E
A
D
S
G
Y
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115030
260
28061
T218
A
R
G
A
D
L
T
T
E
A
D
S
G
Y
T
Dog
Lupus familis
XP_533866
260
27992
T218
A
R
G
A
D
L
T
T
E
A
D
S
G
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z205
269
29213
T227
A
R
G
A
D
L
T
T
E
A
D
S
G
Y
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513323
339
36366
A292
G
G
T
P
L
L
Y
A
V
R
G
N
H
V
K
Chicken
Gallus gallus
NP_001026560
283
30516
R239
C
V
E
A
L
L
A
R
G
A
D
L
T
T
E
Frog
Xenopus laevis
NP_001089411
237
25991
A197
E
V
L
L
E
R
G
A
D
L
T
M
E
A
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197883
387
41776
S346
I
V
K
M
L
L
D
S
G
A
D
M
T
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
93
N.A.
82.1
N.A.
N.A.
56.6
65.7
65.7
N.A.
N.A.
N.A.
N.A.
N.A.
25
Protein Similarity:
100
N.A.
98.4
93.8
N.A.
87.7
N.A.
N.A.
63.1
75.2
75.3
N.A.
N.A.
N.A.
N.A.
N.A.
42.1
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
6.6
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
63
0
0
13
25
0
75
0
0
0
13
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
0
13
0
13
0
75
0
0
0
13
% D
% Glu:
13
0
13
0
13
0
0
0
50
0
0
0
13
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
13
50
0
0
0
13
0
25
0
13
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
13
% K
% Leu:
0
0
13
13
38
88
0
0
0
13
0
13
0
0
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
25
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
50
0
0
0
13
0
13
0
13
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
13
0
0
0
50
0
0
0
% S
% Thr:
0
0
13
0
0
0
50
50
0
0
13
0
25
13
50
% T
% Val:
0
38
0
0
0
0
0
0
13
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _