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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCAN All Species: 13.03
Human Site: T950 Identified Species: 47.78
UniProt: O14594 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14594 NP_004377.2 1321 143093 T950 S V S S G E P T V P W D P S S
Chimpanzee Pan troglodytes Q5IS41 1321 142848 T950 S V S S G E P T V P W D P S S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541924 1326 142924 T955 S V S S G E P T M P G D T P S
Cat Felis silvestris
Mouse Mus musculus P55066 1268 137182 T916 S V S S G E P T G L W D I P S
Rat Rattus norvegicus P55067 1257 135526 S891 H P W S S L A S S M D E V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990071 1290 138859 V918 P T A P H P W V P E G P E A P
Frog Xenopus laevis NP_001104185 3190 348325 G2367 E V E T S E S G L K S E S S T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 76 N.A. 66.1 65.5 N.A. N.A. 45.5 20.6 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 N.A. 83.2 N.A. 74.1 73.5 N.A. N.A. 56.8 29.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 73.3 N.A. 73.3 13.3 N.A. N.A. 0 20 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 80 N.A. 73.3 33.3 N.A. N.A. 13.3 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 0 0 15 0 0 0 0 0 0 29 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 15 58 0 0 0 % D
% Glu: 15 0 15 0 0 72 0 0 0 15 0 29 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 58 0 0 15 15 0 29 0 0 0 0 % G
% His: 15 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 15 0 0 15 15 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 15 15 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 15 0 15 0 15 58 0 15 43 0 15 29 29 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 58 0 58 72 29 0 15 15 15 0 15 0 15 43 72 % S
% Thr: 0 15 0 15 0 0 0 58 0 0 0 0 15 0 15 % T
% Val: 0 72 0 0 0 0 0 15 29 0 0 0 15 0 0 % V
% Trp: 0 0 15 0 0 0 15 0 0 0 43 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _