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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42EP2
All Species:
22.73
Human Site:
T88
Identified Species:
55.56
UniProt:
O14613
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14613
NP_006770.1
210
22484
T88
L
P
F
Q
F
T
R
T
A
T
V
C
G
R
E
Chimpanzee
Pan troglodytes
XP_001169517
210
22488
T88
L
P
F
Q
F
T
R
T
A
T
V
C
G
R
E
Rhesus Macaque
Macaca mulatta
XP_001113902
210
22479
T88
L
P
F
Q
F
T
R
T
A
T
V
C
G
R
E
Dog
Lupus familis
XP_540865
214
22914
T88
L
P
F
Q
F
T
R
T
G
T
L
C
G
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZX9
214
22979
T88
L
P
F
Q
F
T
R
T
T
T
V
C
G
R
E
Rat
Rattus norvegicus
Q5PQP4
214
23030
T88
L
P
F
Q
F
T
R
T
T
T
V
C
G
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510360
257
27876
N89
H
N
E
F
L
R
A
N
S
T
S
D
S
V
F
Chicken
Gallus gallus
XP_426134
253
27922
S89
S
E
F
L
R
A
N
S
T
S
E
S
M
F
T
Frog
Xenopus laevis
NP_001085535
234
25896
D89
L
D
E
E
F
H
S
D
A
I
S
A
S
Y
R
Zebra Danio
Brachydanio rerio
NP_001013549
247
26564
P88
T
A
S
V
C
S
H
P
A
V
S
E
G
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
90.6
N.A.
87.3
86.4
N.A.
38.9
39.5
28.2
49.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
100
93.9
N.A.
92.5
91.1
N.A.
51.7
49.7
43.1
57.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
6.6
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
20
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
0
50
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
60
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% D
% Glu:
0
10
20
10
0
0
0
0
0
0
10
10
0
0
60
% E
% Phe:
0
0
70
10
70
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
70
0
0
% G
% His:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
70
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
60
0
0
0
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
60
0
0
0
0
0
0
60
10
% R
% Ser:
10
0
10
0
0
10
10
10
10
10
30
10
20
10
0
% S
% Thr:
10
0
0
0
0
60
0
60
30
70
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
10
50
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _