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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3D1
All Species:
19.09
Human Site:
S869
Identified Species:
42
UniProt:
O14617
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14617
NP_001070991.1
1153
130158
S869
K
E
K
E
K
K
K
S
P
K
P
K
K
K
K
Chimpanzee
Pan troglodytes
XP_001149712
1153
130142
S869
K
E
K
E
K
K
K
S
P
K
P
K
K
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533956
1153
130053
S870
K
G
K
E
A
R
K
S
S
K
H
K
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O54774
1199
135063
E854
K
T
K
E
R
E
R
E
K
K
D
K
K
G
E
Rat
Rattus norvegicus
NP_001094189
1204
135648
S921
D
H
D
Q
E
R
K
S
S
R
H
K
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038480
1247
140211
S862
K
E
K
D
R
K
R
S
K
E
D
K
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54362
1034
114827
S753
R
V
G
I
T
K
R
S
D
K
Y
L
Q
E
Q
Honey Bee
Apis mellifera
XP_395563
977
111325
G704
P
I
Q
V
V
N
T
G
I
G
E
L
P
P
G
Nematode Worm
Caenorhab. elegans
NP_494570
1251
139932
L904
Q
Q
E
P
A
V
K
L
V
K
E
K
K
K
K
Sea Urchin
Strong. purpuratus
XP_001192784
740
83672
N467
Q
M
A
T
L
L
E
N
T
H
L
L
I
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08951
932
106906
T659
D
E
N
L
D
L
E
T
P
F
L
T
K
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.1
N.A.
86.6
86.8
N.A.
N.A.
N.A.
N.A.
74.5
N.A.
46.4
52
47.1
48.5
Protein Similarity:
100
99.9
N.A.
96.7
N.A.
91.2
91.3
N.A.
N.A.
N.A.
N.A.
83.6
N.A.
60.1
66.5
66.6
57.4
P-Site Identity:
100
93.3
N.A.
66.6
N.A.
40
40
N.A.
N.A.
N.A.
N.A.
60
N.A.
20
0
40
0
P-Site Similarity:
100
100
N.A.
73.3
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
53.3
6.6
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
19
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
10
10
10
0
0
0
10
0
19
0
0
0
0
% D
% Glu:
0
37
10
37
10
10
19
10
0
10
19
0
0
19
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
10
0
10
0
0
0
19
10
% G
% His:
0
10
0
0
0
0
0
0
0
10
19
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
46
0
46
0
19
37
46
0
19
55
0
64
73
55
46
% K
% Leu:
0
0
0
10
10
19
0
10
0
0
19
28
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
0
0
0
0
28
0
19
0
10
10
0
% P
% Gln:
19
10
10
10
0
0
0
0
0
0
0
0
10
0
19
% Q
% Arg:
10
0
0
0
19
19
28
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
55
19
0
0
0
0
0
0
% S
% Thr:
0
10
0
10
10
0
10
10
10
0
0
10
0
0
10
% T
% Val:
0
10
0
10
10
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _