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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3D1 All Species: 17.88
Human Site: S982 Identified Species: 39.33
UniProt: O14617 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14617 NP_001070991.1 1153 130158 S982 R M A R P Q G S S V H D G V P
Chimpanzee Pan troglodytes XP_001149712 1153 130142 S982 R M A R P Q G S S V H D G V P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533956 1153 130053 S982 K L A R P E G S S V H D G V P
Cat Felis silvestris
Mouse Mus musculus O54774 1199 135063 S1028 K M T R P E G S S V H D G V P
Rat Rattus norvegicus NP_001094189 1204 135648 S1033 K M A R P E G S S V H D G V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038480 1247 140211 A1076 K L Q R P D G A G P H D G L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54362 1034 114827 N862 K S A A D K E N L K T P A D L
Honey Bee Apis mellifera XP_395563 977 111325 K809 D T K R K K S K S Q E K Y K K
Nematode Worm Caenorhab. elegans NP_494570 1251 139932 L1021 T S S E Y C R L A A N K T I Y
Sea Urchin Strong. purpuratus XP_001192784 740 83672 Q572 E S A D L E V Q E R A C C I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08951 932 106906 L764 K K P E T I R L N R T D N S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 92.1 N.A. 86.6 86.8 N.A. N.A. N.A. N.A. 74.5 N.A. 46.4 52 47.1 48.5
Protein Similarity: 100 99.9 N.A. 96.7 N.A. 91.2 91.3 N.A. N.A. N.A. N.A. 83.6 N.A. 60.1 66.5 66.6 57.4
P-Site Identity: 100 100 N.A. 80 N.A. 80 86.6 N.A. N.A. N.A. N.A. 40 N.A. 6.6 13.3 0 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 100 N.A. N.A. N.A. N.A. 66.6 N.A. 26.6 20 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 55 10 0 0 0 10 10 10 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 10 10 0 0 % C
% Asp: 10 0 0 10 10 10 0 0 0 0 0 64 0 10 0 % D
% Glu: 10 0 0 19 0 37 10 0 10 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 55 0 10 0 0 0 55 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 55 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 19 0 % I
% Lys: 55 10 10 0 10 19 0 10 0 10 0 19 0 10 10 % K
% Leu: 0 19 0 0 10 0 0 19 10 0 0 0 0 10 28 % L
% Met: 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 10 0 10 0 10 0 0 % N
% Pro: 0 0 10 0 55 0 0 0 0 10 0 10 0 0 46 % P
% Gln: 0 0 10 0 0 19 0 10 0 10 0 0 0 0 0 % Q
% Arg: 19 0 0 64 0 0 19 0 0 19 0 0 0 0 0 % R
% Ser: 0 28 10 0 0 0 10 46 55 0 0 0 0 10 0 % S
% Thr: 10 10 10 0 10 0 0 0 0 0 19 0 10 0 10 % T
% Val: 0 0 0 0 0 0 10 0 0 46 0 0 0 46 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _