KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3D1
All Species:
28.48
Human Site:
Y177
Identified Species:
62.67
UniProt:
O14617
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14617
NP_001070991.1
1153
130158
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Chimpanzee
Pan troglodytes
XP_001149712
1153
130142
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533956
1153
130053
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Cat
Felis silvestris
Mouse
Mus musculus
O54774
1199
135063
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Rat
Rattus norvegicus
NP_001094189
1204
135648
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038480
1247
140211
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54362
1034
114827
L155
L
A
N
D
I
M
T
L
M
S
S
T
K
P
Y
Honey Bee
Apis mellifera
XP_395563
977
111325
T112
D
T
E
L
L
M
L
T
T
N
M
I
R
K
D
Nematode Worm
Caenorhab. elegans
NP_494570
1251
139932
Y177
L
Y
K
I
F
L
K
Y
P
D
A
L
R
P
T
Sea Urchin
Strong. purpuratus
XP_001192784
740
83672
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08951
932
106906
K67
N
S
P
D
L
N
S
K
T
N
A
V
L
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.1
N.A.
86.6
86.8
N.A.
N.A.
N.A.
N.A.
74.5
N.A.
46.4
52
47.1
48.5
Protein Similarity:
100
99.9
N.A.
96.7
N.A.
91.2
91.3
N.A.
N.A.
N.A.
N.A.
83.6
N.A.
60.1
66.5
66.6
57.4
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
13.3
6.6
66.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
33.3
33.3
93.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
19
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
19
0
0
0
0
0
10
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
55
0
0
0
0
0
% E
% Phe:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
64
0
0
0
64
10
0
0
0
0
10
19
0
% K
% Leu:
19
0
0
10
19
64
10
10
0
0
0
64
10
0
10
% L
% Met:
55
0
0
0
0
19
0
0
10
0
10
0
0
0
0
% M
% Asn:
10
0
10
0
0
10
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
64
0
0
0
0
73
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% R
% Ser:
0
10
0
0
0
0
10
0
0
10
64
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
10
19
0
0
10
0
0
10
% T
% Val:
0
0
0
55
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
64
0
0
0
0
0
64
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _