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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3D1
All Species:
23.64
Human Site:
Y724
Identified Species:
52
UniProt:
O14617
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14617
NP_001070991.1
1153
130158
Y724
G
L
P
M
S
D
Q
Y
V
K
L
E
E
E
R
Chimpanzee
Pan troglodytes
XP_001149712
1153
130142
Y724
G
L
P
M
S
D
Q
Y
V
K
L
E
E
E
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533956
1153
130053
Y724
G
M
P
M
S
D
Q
Y
V
K
L
E
E
E
R
Cat
Felis silvestris
Mouse
Mus musculus
O54774
1199
135063
Y724
G
M
P
M
S
D
Q
Y
V
K
L
E
E
Q
R
Rat
Rattus norvegicus
NP_001094189
1204
135648
Y724
G
M
P
M
S
D
Q
Y
V
K
L
E
E
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038480
1247
140211
Y723
G
M
P
M
S
D
Q
Y
V
K
L
E
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54362
1034
114827
D639
L
P
D
G
L
D
L
D
E
W
I
N
A
P
P
Honey Bee
Apis mellifera
XP_395563
977
111325
M591
P
G
L
A
Q
E
L
M
E
T
F
E
G
E
L
Nematode Worm
Caenorhab. elegans
NP_494570
1251
139932
H756
I
P
G
V
V
G
L
H
R
Y
M
E
Q
Q
D
Sea Urchin
Strong. purpuratus
XP_001192784
740
83672
R354
I
L
D
C
L
D
D
R
D
E
S
I
R
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08951
932
106906
S546
N
I
S
Y
Y
S
H
S
V
Q
E
V
L
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.1
N.A.
86.6
86.8
N.A.
N.A.
N.A.
N.A.
74.5
N.A.
46.4
52
47.1
48.5
Protein Similarity:
100
99.9
N.A.
96.7
N.A.
91.2
91.3
N.A.
N.A.
N.A.
N.A.
83.6
N.A.
60.1
66.5
66.6
57.4
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
6.6
13.3
6.6
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
13.3
20
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
73
10
10
10
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
10
0
0
19
10
10
73
55
46
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
55
10
10
10
0
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
19
10
0
0
0
0
0
0
0
0
10
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% K
% Leu:
10
28
10
0
19
0
28
0
0
0
55
0
10
10
19
% L
% Met:
0
37
0
55
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
19
55
0
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
10
0
55
0
0
10
0
0
10
28
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
64
% R
% Ser:
0
0
10
0
55
10
0
10
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
64
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
55
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _