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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCS
All Species:
12.42
Human Site:
Y134
Identified Species:
24.85
UniProt:
O14618
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14618
NP_005116.1
274
29041
Y134
H
G
L
H
V
H
Q
Y
G
D
L
T
N
N
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118002
255
27024
H136
F
N
P
D
G
A
S
H
G
G
P
Q
D
S
D
Dog
Lupus familis
XP_533218
274
28936
F134
H
G
L
H
V
H
Q
F
G
D
L
T
G
N
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU84
274
28893
Y134
H
G
L
H
V
H
Q
Y
G
D
L
T
R
D
C
Rat
Rattus norvegicus
Q9JK72
274
28871
Y134
H
G
L
H
V
H
Q
Y
G
D
L
T
K
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P15107
151
15400
T38
E
G
K
I
E
G
L
T
D
G
L
H
G
F
H
Zebra Danio
Brachydanio rerio
O73872
154
15934
P41
G
E
I
T
G
L
T
P
G
K
H
G
F
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652029
264
27918
S128
H
G
L
H
I
H
E
S
G
D
T
S
A
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34697
180
18682
F67
L
T
P
G
L
H
G
F
H
V
H
Q
Y
G
D
Sea Urchin
Strong. purpuratus
XP_790634
275
28989
P157
G
T
I
D
G
L
S
P
G
E
H
S
L
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23345
152
15096
P39
G
S
V
S
G
L
K
P
G
L
H
G
F
H
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O78310
216
22225
G103
R
I
T
G
L
T
P
G
P
H
G
F
H
L
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89
89
N.A.
86.8
85
N.A.
N.A.
N.A.
28.4
31.7
N.A.
44.8
N.A.
30.2
50.1
Protein Similarity:
100
N.A.
91.2
93.8
N.A.
94.5
93.4
N.A.
N.A.
N.A.
38.3
39
N.A.
63.8
N.A.
40.8
65
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
13.3
6.6
N.A.
53.3
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
13.3
20
N.A.
73.3
N.A.
20
26.6
Percent
Protein Identity:
N.A.
31
N.A.
32.8
N.A.
N.A.
Protein Similarity:
N.A.
39.4
N.A.
46.7
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% C
% Asp:
0
0
0
17
0
0
0
0
9
42
0
0
9
17
17
% D
% Glu:
9
9
0
0
9
0
9
0
0
9
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
17
0
0
0
9
17
9
0
% F
% Gly:
25
50
0
17
34
9
9
9
75
17
9
17
17
17
0
% G
% His:
42
0
0
42
0
50
0
9
9
9
34
9
9
17
17
% H
% Ile:
0
9
17
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
0
9
0
0
9
0
0
% K
% Leu:
9
0
42
0
17
25
9
0
0
9
42
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
9
17
0
% N
% Pro:
0
0
17
0
0
0
9
25
9
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
34
0
0
0
0
17
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% R
% Ser:
0
9
0
9
0
0
17
9
0
0
0
17
0
9
0
% S
% Thr:
0
17
9
9
0
9
9
9
0
0
9
34
0
0
0
% T
% Val:
0
0
9
0
34
0
0
0
0
9
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _