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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP3
All Species:
32.12
Human Site:
Y755
Identified Species:
70.67
UniProt:
O14638
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14638
NP_005012.2
875
100124
Y755
G
P
I
F
D
Y
N
Y
D
G
H
F
D
A
P
Chimpanzee
Pan troglodytes
XP_518741
875
100145
Y755
G
P
I
F
D
Y
N
Y
D
G
H
F
D
A
P
Rhesus Macaque
Macaca mulatta
XP_001103445
874
99855
Y754
G
P
I
F
D
Y
N
Y
D
G
H
F
D
A
P
Dog
Lupus familis
XP_532050
889
102239
Y769
G
P
V
F
D
Y
N
Y
D
G
H
F
D
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6DYE8
874
98630
Y754
G
P
I
F
D
Y
N
Y
D
G
H
F
D
A
P
Rat
Rattus norvegicus
P97675
875
99053
Y755
G
P
I
F
D
Y
N
Y
D
G
H
F
D
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505967
868
99060
Y748
G
P
I
F
D
Y
N
Y
D
G
H
F
D
T
L
Chicken
Gallus gallus
XP_424539
912
103729
S790
G
P
V
F
D
Y
D
S
D
G
I
Y
D
T
P
Frog
Xenopus laevis
Q6AX80
452
51293
Y338
S
M
L
G
D
H
G
Y
D
N
D
L
H
S
M
Zebra Danio
Brachydanio rerio
Q566N0
459
51584
L346
D
H
G
Y
D
N
T
L
P
S
M
H
P
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90754
829
93146
K710
K
S
M
E
Y
L
N
K
F
G
K
M
Y
V
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97
80.6
N.A.
80.6
81.4
N.A.
69.5
51.4
20.9
21.3
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.6
98.2
88.4
N.A.
90.4
90.1
N.A.
82.5
67
34.6
34.7
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
60
20
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
40
13.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
91
0
10
0
82
0
10
0
73
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
73
0
0
0
0
10
0
0
64
0
10
0
% F
% Gly:
73
0
10
10
0
0
10
0
0
82
0
0
0
0
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
64
10
10
0
0
% H
% Ile:
0
0
55
0
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
10
0
0
10
0
10
0
0
0
10
0
0
19
% L
% Met:
0
10
10
0
0
0
0
0
0
0
10
10
0
0
10
% M
% Asn:
0
0
0
0
0
10
73
0
0
10
0
0
0
0
0
% N
% Pro:
0
73
0
0
0
0
0
0
10
0
0
0
10
0
64
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
10
0
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
19
0
% T
% Val:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
73
0
73
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _