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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP3
All Species:
27.88
Human Site:
Y867
Identified Species:
61.33
UniProt:
O14638
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14638
NP_005012.2
875
100124
Y867
E
I
L
Q
L
K
T
Y
L
P
T
F
E
T
T
Chimpanzee
Pan troglodytes
XP_518741
875
100145
Y867
E
I
L
Q
L
K
T
Y
L
P
T
F
E
T
T
Rhesus Macaque
Macaca mulatta
XP_001103445
874
99855
Y866
E
I
L
Q
L
K
T
Y
L
P
T
F
E
T
T
Dog
Lupus familis
XP_532050
889
102239
Y881
E
I
L
Q
L
K
T
Y
L
P
T
F
E
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6DYE8
874
98630
Y866
Q
I
L
Q
L
K
T
Y
L
P
T
F
E
T
I
Rat
Rattus norvegicus
P97675
875
99053
Y867
E
I
L
Q
L
K
T
Y
L
P
T
F
E
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505967
868
99060
F860
E
V
L
K
L
K
T
F
L
P
T
F
E
T
I
Chicken
Gallus gallus
XP_424539
912
103729
Y905
D
I
L
Q
L
K
T
Y
L
P
T
F
E
T
V
Frog
Xenopus laevis
Q6AX80
452
51293
Q444
P
F
S
R
L
Q
F
Q
D
D
D
D
P
L
I
Zebra Danio
Brachydanio rerio
Q566N0
459
51584
G452
R
L
E
L
D
D
D
G
D
D
E
P
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90754
829
93146
T818
A
L
S
Q
N
Q
N
T
I
I
R
R
K
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97
80.6
N.A.
80.6
81.4
N.A.
69.5
51.4
20.9
21.3
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.6
98.2
88.4
N.A.
90.4
90.1
N.A.
82.5
67
34.6
34.7
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
73.3
86.6
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
20
6.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
10
10
0
19
19
10
10
0
0
0
% D
% Glu:
55
0
10
0
0
0
0
0
0
0
10
0
73
0
10
% E
% Phe:
0
10
0
0
0
0
10
10
0
0
0
73
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
64
0
0
0
0
0
0
10
10
0
0
0
10
46
% I
% Lys:
0
0
0
10
0
73
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
19
73
10
82
0
0
0
73
0
0
0
10
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
73
0
10
10
0
0
% P
% Gln:
10
0
0
73
0
19
0
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
73
10
0
0
73
0
0
73
28
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _