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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD1 All Species: 23.03
Human Site: S216 Identified Species: 42.22
UniProt: O14646 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14646 NP_001261.2 1710 196688 S216 K K R Q I D S S E E D D D E E
Chimpanzee Pan troglodytes XP_517850 1710 196736 S216 K K R Q I D S S E E D D D E E
Rhesus Macaque Macaca mulatta XP_001097125 1712 197047 S218 K K R Q I D S S E E E E D E E
Dog Lupus familis XP_848459 1711 196992 S215 K K R Q I D S S E E E D D E E
Cat Felis silvestris
Mouse Mus musculus P40201 1711 196392 S214 Q K K R Q I D S S E D E D D E
Rat Rattus norvegicus Q9JIX5 2581 290674 L511 K K S S G E R L K E E K P K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513135 1807 208022 D217 K R Q I D S S D E D D D D D D
Chicken Gallus gallus B6ZLK2 1719 197507 S212 Q K K R Q L D S S E E E E D D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 S581 K R K R N P S S D H S D V D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KU24 1883 211809 F255 Q R R R V K P F S S E D S D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 C291 T R A Y H V A C I D E N M E Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 D33 D D F V P K K D R T F E Q V E
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 K117 K P K S Q S E K Q S T V K I P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 98.3 N.A. 95.7 23.3 N.A. 88.6 92.4 N.A. 23.6 N.A. 45.6 N.A. 26.3 N.A.
Protein Similarity: 100 99.8 99.8 99.3 N.A. 97.9 38.9 N.A. 91.6 95.9 N.A. 38.8 N.A. 62.1 N.A. 43.8 N.A.
P-Site Identity: 100 100 86.6 93.3 N.A. 40 20 N.A. 40 20 N.A. 26.6 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 73.3 53.3 N.A. 73.3 73.3 N.A. 60 N.A. 60 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 31.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 8 31 16 16 8 16 31 47 47 39 24 % D
% Glu: 0 0 0 0 0 8 8 0 39 54 47 31 8 39 47 % E
% Phe: 0 0 8 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 31 8 0 0 8 0 0 0 0 8 0 % I
% Lys: 62 54 31 0 0 16 8 8 8 0 0 8 8 8 8 % K
% Leu: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 8 0 0 8 8 8 0 0 0 0 0 8 0 8 % P
% Gln: 24 0 8 31 24 0 0 0 8 0 0 0 8 0 8 % Q
% Arg: 0 31 39 31 0 0 8 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 8 16 0 16 47 54 24 16 8 0 8 0 0 % S
% Thr: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % T
% Val: 0 0 0 8 8 8 0 0 0 0 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _