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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD1
All Species:
30
Human Site:
T250
Identified Species:
55
UniProt:
O14646
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14646
NP_001261.2
1710
196688
T250
K
E
D
E
E
M
K
T
D
S
D
D
L
L
E
Chimpanzee
Pan troglodytes
XP_517850
1710
196736
T250
K
E
D
E
E
M
K
T
D
S
D
D
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001097125
1712
197047
T252
K
E
D
E
E
M
K
T
D
S
D
D
L
L
E
Dog
Lupus familis
XP_848459
1711
196992
T249
K
E
D
E
E
M
K
T
D
S
D
D
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P40201
1711
196392
T248
K
E
D
E
E
M
K
T
D
S
D
D
L
L
E
Rat
Rattus norvegicus
Q9JIX5
2581
290674
K545
P
V
V
G
K
K
R
K
R
N
T
S
S
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513135
1807
208022
T251
K
E
D
E
E
M
K
T
D
S
D
D
L
L
E
Chicken
Gallus gallus
B6ZLK2
1719
197507
T246
K
E
A
E
E
T
K
T
D
S
D
D
L
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
K615
N
R
Q
V
K
R
K
K
Y
T
E
D
L
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
T289
E
A
S
E
D
E
A
T
D
S
E
D
L
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
K325
I
V
E
E
E
P
A
K
A
N
M
D
Y
C
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
C67
N
L
V
S
C
N
T
C
T
Y
A
F
H
A
K
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
D151
D
D
L
L
E
S
E
D
D
Y
G
S
E
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
98.3
N.A.
95.7
23.3
N.A.
88.6
92.4
N.A.
23.6
N.A.
45.6
N.A.
26.3
N.A.
Protein Similarity:
100
99.8
99.8
99.3
N.A.
97.9
38.9
N.A.
91.6
95.9
N.A.
38.8
N.A.
62.1
N.A.
43.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
86.6
N.A.
20
N.A.
53.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
86.6
N.A.
40
N.A.
73.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.2
49.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
16
0
8
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
8
8
47
0
8
0
0
8
70
0
54
77
0
16
0
% D
% Glu:
8
54
8
70
70
8
8
0
0
0
16
0
8
8
62
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
54
0
0
0
16
8
62
24
0
0
0
0
0
0
8
% K
% Leu:
0
8
8
8
0
0
0
0
0
0
0
0
70
62
0
% L
% Met:
0
0
0
0
0
47
0
0
0
0
8
0
0
0
0
% M
% Asn:
16
0
0
0
0
8
0
0
0
16
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% R
% Ser:
0
0
8
8
0
8
0
0
0
62
0
16
8
0
0
% S
% Thr:
0
0
0
0
0
8
8
62
8
8
8
0
0
0
0
% T
% Val:
0
16
16
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
16
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _