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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD2 All Species: 14.24
Human Site: S1235 Identified Species: 24.1
UniProt: O14647 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14647 NP_001262.3 1828 211344 S1235 E F E M L H K S I P V D P E E
Chimpanzee Pan troglodytes XP_001170676 1828 211351 S1235 E F E M L H K S I P V D P E E
Rhesus Macaque Macaca mulatta XP_001097125 1712 197047 R1169 K S E T D L R R L G E L V H N
Dog Lupus familis XP_849509 1827 211238 S1235 E F E M L H K S I P V D P E E
Cat Felis silvestris
Mouse Mus musculus P40201 1711 196392 E1168 T D L R R L G E L V H N G C V
Rat Rattus norvegicus Q9JIX5 2581 290674 R1582 N K V L L R V R M L Y Y L R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513135 1807 208022 S1228 E L V P L H K S I P S D P E E
Chicken Gallus gallus Q06A37 3011 338194 E1971 Q K W T R R E E A D F Y R V V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 V1625 C N K V L L R V R M L Y Y L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 W1438 Q D A F N S Q W L V R D L R G
Honey Bee Apis mellifera XP_001120496 1675 191695 Q1132 E L R F L G D Q L K T R C D T
Nematode Worm Caenorhab. elegans Q22516 1787 205237 E1215 E Q D P N Y W E K L L K H H Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 S842 A Q R V A A E S K S S A G N S
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 Y926 K Q F E V T D Y K A D I D W D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 58.1 98.4 N.A. 57.1 23.3 N.A. 58.5 22.1 N.A. 22.2 N.A. 27.6 50 28.3 N.A.
Protein Similarity: 100 99.9 71.1 99.3 N.A. 70.4 39.6 N.A. 72.7 36.4 N.A. 39 N.A. 45.6 64.7 48.1 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 0 6.6 N.A. 73.3 0 N.A. 6.6 N.A. 6.6 13.3 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 13.3 26.6 N.A. 73.3 13.3 N.A. 40 N.A. 26.6 26.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 31.7 N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 48.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 8 0 0 8 8 0 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 15 8 0 8 0 15 0 0 8 8 36 8 8 8 % D
% Glu: 43 0 29 8 0 0 15 22 0 0 8 0 0 29 29 % E
% Phe: 0 22 8 15 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 0 0 8 0 0 15 0 8 % G
% His: 0 0 0 0 0 29 0 0 0 0 8 0 8 15 0 % H
% Ile: 0 0 0 0 0 0 0 0 29 0 0 8 0 0 0 % I
% Lys: 15 15 8 0 0 0 29 0 22 8 0 8 0 0 8 % K
% Leu: 0 15 8 8 50 22 0 0 29 15 15 8 15 8 0 % L
% Met: 0 0 0 22 0 0 0 0 8 8 0 0 0 0 0 % M
% Asn: 8 8 0 0 15 0 0 0 0 0 0 8 0 8 8 % N
% Pro: 0 0 0 15 0 0 0 0 0 29 0 0 29 0 0 % P
% Gln: 15 22 0 0 0 0 8 8 0 0 0 0 0 0 8 % Q
% Arg: 0 0 15 8 15 15 15 15 8 0 8 8 8 15 0 % R
% Ser: 0 8 0 0 0 8 0 36 0 8 15 0 0 0 8 % S
% Thr: 8 0 0 15 0 8 0 0 0 0 8 0 0 0 8 % T
% Val: 0 0 15 15 8 0 8 8 0 15 22 0 8 8 15 % V
% Trp: 0 0 8 0 0 0 8 8 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 8 0 8 0 0 8 22 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _