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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK3
All Species:
15.15
Human Site:
S354
Identified Species:
27.78
UniProt:
O14649
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14649
NP_002237.1
394
43518
S354
P
G
G
G
G
R
Y
S
D
T
P
S
R
R
C
Chimpanzee
Pan troglodytes
XP_001152552
330
36183
C291
V
G
S
A
S
V
S
C
H
V
H
K
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001087754
445
48978
E354
C
E
S
R
L
S
V
E
K
M
A
A
H
V
P
Dog
Lupus familis
XP_540117
395
43148
S355
P
G
G
G
G
R
Y
S
D
T
P
S
H
R
C
Cat
Felis silvestris
Mouse
Mus musculus
O35111
409
45050
S369
P
G
G
G
G
R
Y
S
D
T
P
S
H
P
C
Rat
Rattus norvegicus
O54912
411
45258
S371
P
G
G
G
G
R
Y
S
D
T
P
S
H
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509654
368
40454
T329
S
P
G
A
G
C
Y
T
D
T
P
S
H
R
C
Chicken
Gallus gallus
XP_425942
374
42568
E335
H
S
I
S
Y
K
I
E
E
I
S
P
S
T
L
Frog
Xenopus laevis
Q63ZI0
374
42700
E335
H
S
I
S
Y
K
I
E
E
I
S
P
S
T
L
Zebra Danio
Brachydanio rerio
NP_001025333
390
43702
V350
E
H
S
E
T
S
D
V
L
H
S
N
G
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649891
340
37822
L301
E
N
D
E
T
A
S
L
C
S
C
T
C
M
G
Honey Bee
Apis mellifera
XP_394509
367
40863
I328
V
R
R
S
P
G
K
I
S
H
L
L
P
M
Q
Nematode Worm
Caenorhab. elegans
O17185
329
36973
L290
P
L
S
D
N
V
S
L
A
S
C
S
C
Y
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
80
94.4
N.A.
88.7
88.5
N.A.
73.8
57.6
59.3
72.5
N.A.
42.8
44.6
46.4
N.A.
Protein Similarity:
100
58.3
83.1
95.9
N.A.
90.7
90.2
N.A.
78.9
69.8
70.8
82.2
N.A.
57.6
61.1
60.1
N.A.
P-Site Identity:
100
6.6
0
93.3
N.A.
86.6
86.6
N.A.
60
0
0
0
N.A.
0
0
13.3
N.A.
P-Site Similarity:
100
6.6
6.6
93.3
N.A.
86.6
86.6
N.A.
66.6
13.3
13.3
6.6
N.A.
13.3
0
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
8
0
0
8
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
8
0
8
8
0
16
0
16
8
39
% C
% Asp:
0
0
8
8
0
0
8
0
39
0
0
0
0
0
0
% D
% Glu:
16
8
0
16
0
0
0
24
16
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
39
39
31
39
8
0
0
0
0
0
0
8
0
8
% G
% His:
16
8
0
0
0
0
0
0
8
16
8
0
39
0
0
% H
% Ile:
0
0
16
0
0
0
16
8
0
16
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
16
8
0
8
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
8
0
0
16
8
0
8
8
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
39
8
0
0
8
0
0
0
0
0
39
16
8
16
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
8
8
8
0
31
0
0
0
0
0
0
8
24
8
% R
% Ser:
8
16
31
24
8
16
24
31
8
16
24
47
16
0
0
% S
% Thr:
0
0
0
0
16
0
0
8
0
39
0
8
0
16
0
% T
% Val:
16
0
0
0
0
16
8
8
0
8
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
39
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _