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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOSR2
All Species:
21.82
Human Site:
S40
Identified Species:
40
UniProt:
O14653
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14653
NP_001012529.1
212
24775
S40
V
E
N
E
I
Q
A
S
I
D
Q
I
F
S
R
Chimpanzee
Pan troglodytes
XP_001135292
212
24759
S40
V
E
N
E
I
Q
A
S
I
D
Q
I
F
S
R
Rhesus Macaque
Macaca mulatta
XP_001115716
212
24826
S40
V
E
N
E
I
Q
A
S
I
D
Q
I
F
S
R
Dog
Lupus familis
XP_853038
212
24608
S40
V
E
N
E
I
Q
A
S
I
D
Q
I
F
N
H
Cat
Felis silvestris
Mouse
Mus musculus
O35166
212
24707
S40
V
E
N
E
I
Q
A
S
I
E
Q
I
F
S
H
Rat
Rattus norvegicus
O35165
212
24589
S40
V
E
N
E
I
Q
A
S
I
D
Q
I
F
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001074333
140
16958
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955982
212
24551
R40
L
E
N
E
L
Q
A
R
I
D
Q
I
F
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRL2
216
24815
K40
V
E
N
G
I
Q
L
K
I
T
Q
A
N
A
N
Honey Bee
Apis mellifera
XP_396365
212
24355
K41
I
E
N
S
I
E
S
K
I
N
L
I
N
S
N
Nematode Worm
Caenorhab. elegans
P41941
213
24632
G40
V
V
V
Q
C
I
Y
G
D
V
I
T
L
K
E
Sea Urchin
Strong. purpuratus
XP_794856
214
24852
R42
A
E
N
E
I
K
A
R
L
D
N
L
A
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJL6
225
25610
K51
P
D
L
A
S
S
V
K
R
D
I
T
E
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.1
90
N.A.
88.2
91
N.A.
N.A.
49.5
N.A.
75.4
N.A.
40.7
49
32.3
50.4
Protein Similarity:
100
100
99
96.2
N.A.
93.8
96.2
N.A.
N.A.
58.4
N.A.
89.6
N.A.
62.9
69.8
55.4
69.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
N.A.
0
N.A.
66.6
N.A.
46.6
40
6.6
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
93.3
N.A.
53.3
66.6
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
62
0
0
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
62
0
0
0
0
0
% D
% Glu:
0
77
0
62
0
8
0
0
0
8
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
8
0
0
0
70
8
0
0
70
0
16
62
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
24
0
0
0
0
0
8
0
% K
% Leu:
8
0
8
0
8
0
8
0
8
0
8
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
77
0
0
0
0
0
0
8
8
0
16
16
24
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
62
0
0
0
0
62
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
31
% R
% Ser:
0
0
0
8
8
8
8
47
0
0
0
0
0
54
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
16
0
0
0
% T
% Val:
62
8
8
0
0
0
8
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _