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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOSR2 All Species: 36.06
Human Site: T110 Identified Species: 66.11
UniProt: O14653 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14653 NP_001012529.1 212 24775 T110 E L L S R T F T T N D S D T T
Chimpanzee Pan troglodytes XP_001135292 212 24759 T110 E L L S R T F T T N D S D T T
Rhesus Macaque Macaca mulatta XP_001115716 212 24826 T110 E L L S R T F T T N D S D T T
Dog Lupus familis XP_853038 212 24608 T110 A L L S R T F T T N D S D T T
Cat Felis silvestris
Mouse Mus musculus O35166 212 24707 T110 E L L S R T F T T N D S D T T
Rat Rattus norvegicus O35165 212 24589 T110 E L L S R T F T T N D S D T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001074333 140 16958 L48 I D K V F S N L E R L E I L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_955982 212 24551 T110 E L L S R S F T T N D A D T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRL2 216 24815 T110 Q L L N H R F T A N S A Q P E
Honey Bee Apis mellifera XP_396365 212 24355 T111 A L L S R T F T T N D H V D I
Nematode Worm Caenorhab. elegans P41941 213 24632 R111 E L L R T R Y R P N D T A L S
Sea Urchin Strong. purpuratus XP_794856 214 24852 T112 D L L T R R F T A N D D N T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJL6 225 25610 G124 D L L G R A S G E G A H I L Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.1 90 N.A. 88.2 91 N.A. N.A. 49.5 N.A. 75.4 N.A. 40.7 49 32.3 50.4
Protein Similarity: 100 100 99 96.2 N.A. 93.8 96.2 N.A. N.A. 58.4 N.A. 89.6 N.A. 62.9 69.8 55.4 69.1
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 0 N.A. 80 N.A. 33.3 66.6 33.3 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 13.3 N.A. 100 N.A. 53.3 66.6 53.3 80
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 0 8 0 0 16 0 8 16 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 0 0 0 0 0 0 0 0 77 8 54 8 0 % D
% Glu: 54 0 0 0 0 0 0 0 16 0 0 8 0 0 8 % E
% Phe: 0 0 0 0 8 0 77 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 16 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 16 0 8 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 93 93 0 0 0 0 8 0 0 8 0 0 24 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 85 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % Q
% Arg: 0 0 0 8 77 24 0 8 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 62 0 16 8 0 0 0 8 47 0 0 31 % S
% Thr: 0 0 0 8 8 54 0 77 62 0 0 8 0 62 47 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _