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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOR1A
All Species:
21.82
Human Site:
Y290
Identified Species:
43.64
UniProt:
O14656
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14656
NP_000104.1
332
37809
Y290
V
E
M
Q
S
R
G
Y
E
I
D
E
D
I
V
Chimpanzee
Pan troglodytes
XP_001164380
332
37804
Y290
V
E
M
Q
S
R
G
Y
E
I
D
E
D
I
V
Rhesus Macaque
Macaca mulatta
XP_001118658
442
49103
Y400
V
E
M
Q
S
R
G
Y
E
T
N
E
D
I
V
Dog
Lupus familis
XP_548417
421
47300
F379
V
E
M
Q
S
R
G
F
D
I
D
E
D
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER39
333
37811
Y291
V
E
M
Q
S
R
G
Y
E
V
D
E
D
I
I
Rat
Rattus norvegicus
Q6AYR4
321
35853
G280
L
N
E
L
A
Q
L
G
L
E
P
R
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508626
335
38089
Y293
V
E
M
E
S
R
G
Y
V
V
D
E
D
I
V
Chicken
Gallus gallus
NP_001025858
344
39190
Y302
V
E
I
E
S
R
G
Y
A
V
D
E
D
I
L
Frog
Xenopus laevis
Q68F68
314
35927
Q272
V
R
T
E
M
V
Q
Q
G
L
E
P
E
E
V
Zebra Danio
Brachydanio rerio
NP_001124104
323
37002
I281
A
E
M
E
H
L
E
I
P
K
N
D
D
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77277
340
38152
R295
A
E
L
L
R
W
R
R
D
P
K
Q
A
N
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95NU5
356
40795
R297
A
Y
L
R
K
R
G
R
G
D
L
V
S
N
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
65.8
73.6
N.A.
90.6
41.5
N.A.
83.8
72.6
45.7
47.8
N.A.
33.2
N.A.
36.5
N.A.
Protein Similarity:
100
99.6
69.2
76.4
N.A.
95.8
64.4
N.A.
90.7
84.5
65.6
66.8
N.A.
55.8
N.A.
54.2
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
86.6
6.6
N.A.
80
66.6
13.3
20
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
33.3
N.A.
93.3
93.3
40
46.6
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
9
0
0
0
9
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
17
9
50
9
67
0
0
% D
% Glu:
0
75
9
34
0
0
9
0
34
9
9
59
17
17
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
67
9
17
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
25
0
0
0
59
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
9
9
0
0
0
0
% K
% Leu:
9
0
17
17
0
9
9
0
9
9
9
0
0
9
9
% L
% Met:
0
0
59
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
17
0
0
17
9
% N
% Pro:
0
0
0
0
0
0
0
0
9
9
9
9
0
0
0
% P
% Gln:
0
0
0
42
0
9
9
9
0
0
0
9
0
0
0
% Q
% Arg:
0
9
0
9
9
67
9
17
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
59
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
67
0
0
0
0
9
0
0
9
25
0
9
0
0
67
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _