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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TOR1B All Species: 16.97
Human Site: T222 Identified Species: 37.33
UniProt: O14657 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14657 NP_055321.1 336 37979 T222 N A G G D L I T K T A L D F W
Chimpanzee Pan troglodytes XP_001164236 336 37946 T222 N A G G D L I T K T A L D F W
Rhesus Macaque Macaca mulatta XP_001107456 336 37928 T222 N A G G D L I T K T A L D F W
Dog Lupus familis XP_548418 307 34581 L203 R K A I F I F L R K R E D I Q
Cat Felis silvestris
Mouse Mus musculus Q9ER41 336 37859 T222 N A G G D L I T K T A L D F W
Rat Rattus norvegicus Q6AYR4 321 35853 N206 N T G G E Q I N Q V A L E A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508626 335 38089 T218 N A G A E R I T D V A L D F W
Chicken Gallus gallus
Frog Xenopus laevis Q68F68 314 35927 N199 N A G G D D I N E V A L D F W
Zebra Danio Brachydanio rerio Q568B8 409 46986 H301 I L I S N L G H E D I T K F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77277 340 38152 A221 N T A G S H I A S H L G S V M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95NU5 356 40795 A223 N K G G G E I A R I T K E Q Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.1 81.8 N.A. 87.5 40.7 N.A. 63.9 N.A. 45.5 21.5 N.A. 34.1 N.A. 35.9 N.A.
Protein Similarity: 100 100 99.4 85.7 N.A. 93.1 60.7 N.A. 79.4 N.A. 62.7 37.9 N.A. 54.4 N.A. 52.5 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 46.6 N.A. 66.6 N.A. 73.3 13.3 N.A. 20 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 66.6 N.A. 73.3 N.A. 80 26.6 N.A. 20 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 55 19 10 0 0 0 19 0 0 64 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 46 10 0 0 10 10 0 0 64 0 0 % D
% Glu: 0 0 0 0 19 10 0 0 19 0 0 10 19 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 0 0 0 0 0 64 0 % F
% Gly: 0 0 73 73 10 0 10 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 0 % H
% Ile: 10 0 10 10 0 10 82 0 0 10 10 0 0 10 0 % I
% Lys: 0 19 0 0 0 0 0 0 37 10 0 10 10 0 0 % K
% Leu: 0 10 0 0 0 46 0 10 0 0 10 64 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 82 0 0 0 10 0 0 19 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 10 0 0 0 0 10 10 % Q
% Arg: 10 0 0 0 0 10 0 0 19 0 10 0 0 0 0 % R
% Ser: 0 0 0 10 10 0 0 0 10 0 0 0 10 0 0 % S
% Thr: 0 19 0 0 0 0 0 46 0 37 10 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 28 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _