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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCD4 All Species: 17.88
Human Site: T259 Identified Species: 35.76
UniProt: O14678 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14678 NP_005041.1 606 68597 T259 R L Q R L L Q T Q R E L M S K
Chimpanzee Pan troglodytes XP_001156286 606 68643 T259 R L Q R L L Q T Q R E L M S K
Rhesus Macaque Macaca mulatta XP_001093730 606 68571 T259 R L Q I L L Q T Q R E L M S K
Dog Lupus familis XP_547903 606 68791 T259 R L Q R L L Q T Q R E L M S K
Cat Felis silvestris
Mouse Mus musculus O89016 606 68531 T259 R L Q R L L Q T Q R E L M S R
Rat Rattus norvegicus P16970 659 75297 F306 L V E H L H N F I F F R F S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421264 542 61623 G210 I N T F D Y L G S I L S Y V I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070185 277 32794
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_506620 660 74981 Q252 L K N L I E T Q K S L T E W R
Sea Urchin Strong. purpuratus XP_001189079 361 40704 L29 Q T I L F F L L L L I A G G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94FB9 1337 149558 M968 G G A R E K A M V D K K F R A
Baker's Yeast Sacchar. cerevisiae P41909 870 100007 L434 V L M E K M L L V D K V K F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.1 91.2 N.A. 89.4 27.6 N.A. N.A. 67.8 N.A. 31.8 N.A. N.A. N.A. 38.1 31.1
Protein Similarity: 100 99.1 97.8 94.7 N.A. 92.7 47.3 N.A. N.A. 76.9 N.A. 37.6 N.A. N.A. N.A. 58.6 41.9
P-Site Identity: 100 100 93.3 100 N.A. 93.3 13.3 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 100 93.3 100 N.A. 100 26.6 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 21.6 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 31.7 39.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 9 0 0 0 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 17 0 0 0 0 0 % D
% Glu: 0 0 9 9 9 9 0 0 0 0 42 0 9 0 9 % E
% Phe: 0 0 0 9 9 9 0 9 0 9 9 0 17 9 0 % F
% Gly: 9 9 0 0 0 0 0 9 0 0 0 0 9 9 9 % G
% His: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 9 9 0 0 0 9 9 9 0 0 0 9 % I
% Lys: 0 9 0 0 9 9 0 0 9 0 17 9 9 0 34 % K
% Leu: 17 50 0 17 50 42 25 17 9 9 17 42 0 0 0 % L
% Met: 0 0 9 0 0 9 0 9 0 0 0 0 42 0 9 % M
% Asn: 0 9 9 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 42 0 0 0 42 9 42 0 0 0 0 0 0 % Q
% Arg: 42 0 0 42 0 0 0 0 0 42 0 9 0 9 17 % R
% Ser: 0 0 0 0 0 0 0 0 9 9 0 9 0 50 0 % S
% Thr: 0 9 9 0 0 0 9 42 0 0 0 9 0 0 0 % T
% Val: 9 9 0 0 0 0 0 0 17 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _