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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EI24 All Species: 30.3
Human Site: S317 Identified Species: 74.07
UniProt: O14681 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14681 NP_001007278.1 340 38965 S317 Y L Q S A L S S S T S A E K F
Chimpanzee Pan troglodytes XP_001146845 340 38916 S317 Y L Q S A L S S S T S A E K F
Rhesus Macaque Macaca mulatta XP_001111212 340 38916 S317 Y L Q S A L S S S T S A E K F
Dog Lupus familis XP_546419 340 38854 S317 Y L Q S A L S S S T S A E K F
Cat Felis silvestris
Mouse Mus musculus Q61070 340 38914 S317 Y L Q S A L S S S S S A E K F
Rat Rattus norvegicus Q4KM77 340 38874 S317 Y L Q S A L S S S S S A E K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519550 392 42815 S369 Y L Q T A L S S S A S A E K L
Chicken Gallus gallus
Frog Xenopus laevis NP_001088433 340 39103 S317 Y L Q S T L S S S G S S E K L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395483 318 35920 L296 V C D C P L K L F S P V I A I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201462 319 36692 V297 Q V R I F S F V V G V A N K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.1 99.1 N.A. 98.2 98.2 N.A. 61.2 N.A. 89.1 N.A. N.A. N.A. 43.8 N.A. 46.7
Protein Similarity: 100 99.7 99.7 99.4 N.A. 99.1 99.4 N.A. 65.5 N.A. 93.8 N.A. N.A. N.A. 60.8 N.A. 67
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 N.A. 73.3 N.A. N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 N.A. 80 N.A. N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 70 0 0 0 0 10 0 80 0 10 0 % A
% Cys: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 60 % F
% Gly: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 90 0 % K
% Leu: 0 80 0 0 0 90 0 10 0 0 0 0 0 0 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 10 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 70 0 10 80 80 80 30 80 10 0 0 0 % S
% Thr: 0 0 0 10 10 0 0 0 0 40 0 0 0 0 0 % T
% Val: 10 10 0 0 0 0 0 10 10 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _