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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EI24
All Species:
26.97
Human Site:
S46
Identified Species:
65.93
UniProt:
O14681
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14681
NP_001007278.1
340
38965
S46
E
Q
R
R
R
R
A
S
S
V
L
A
Q
R
R
Chimpanzee
Pan troglodytes
XP_001146845
340
38916
S46
E
Q
R
R
R
R
A
S
S
V
L
A
Q
R
R
Rhesus Macaque
Macaca mulatta
XP_001111212
340
38916
S46
E
Q
R
R
R
R
A
S
S
I
L
A
Q
R
R
Dog
Lupus familis
XP_546419
340
38854
S46
E
Q
R
R
R
R
A
S
S
V
L
A
Q
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61070
340
38914
S46
E
Q
R
R
R
R
A
S
S
L
L
A
Q
R
R
Rat
Rattus norvegicus
Q4KM77
340
38874
S46
E
Q
R
R
R
R
A
S
S
L
L
A
Q
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519550
392
42815
G83
S
R
P
Y
Q
L
P
G
A
V
V
P
V
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088433
340
39103
S46
E
Q
R
K
R
R
A
S
S
A
L
A
Q
R
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395483
318
35920
P39
I
N
E
K
L
F
K
P
P
L
N
K
T
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201462
319
36692
M40
M
E
K
I
Q
E
E
M
R
K
K
R
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
99.1
N.A.
98.2
98.2
N.A.
61.2
N.A.
89.1
N.A.
N.A.
N.A.
43.8
N.A.
46.7
Protein Similarity:
100
99.7
99.7
99.4
N.A.
99.1
99.4
N.A.
65.5
N.A.
93.8
N.A.
N.A.
N.A.
60.8
N.A.
67
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
86.6
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
N.A.
93.3
N.A.
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
70
0
10
10
0
70
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
10
10
0
0
10
10
0
0
0
0
0
10
20
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
10
20
0
0
10
0
0
10
10
10
0
0
10
% K
% Leu:
0
0
0
0
10
10
0
0
0
30
70
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
10
10
0
0
10
0
0
0
% P
% Gln:
0
70
0
0
20
0
0
0
0
0
0
0
70
0
0
% Q
% Arg:
0
10
70
60
70
70
0
0
10
0
0
10
0
70
80
% R
% Ser:
10
0
0
0
0
0
0
70
70
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
40
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _