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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EI24 All Species: 26.67
Human Site: S47 Identified Species: 65.19
UniProt: O14681 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14681 NP_001007278.1 340 38965 S47 Q R R R R A S S V L A Q R R A
Chimpanzee Pan troglodytes XP_001146845 340 38916 S47 Q R R R R A S S V L A Q R R A
Rhesus Macaque Macaca mulatta XP_001111212 340 38916 S47 Q R R R R A S S I L A Q R R A
Dog Lupus familis XP_546419 340 38854 S47 Q R R R R A S S V L A Q R R A
Cat Felis silvestris
Mouse Mus musculus Q61070 340 38914 S47 Q R R R R A S S L L A Q R R P
Rat Rattus norvegicus Q4KM77 340 38874 S47 Q R R R R A S S L L A Q R R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519550 392 42815 A84 R P Y Q L P G A V V P V G R E
Chicken Gallus gallus
Frog Xenopus laevis NP_001088433 340 39103 S47 Q R K R R A S S A L A Q R R A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395483 318 35920 P40 N E K L F K P P L N K T E S H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201462 319 36692 R41 E K I Q E E M R K K R E E K M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.1 99.1 N.A. 98.2 98.2 N.A. 61.2 N.A. 89.1 N.A. N.A. N.A. 43.8 N.A. 46.7
Protein Similarity: 100 99.7 99.7 99.4 N.A. 99.1 99.4 N.A. 65.5 N.A. 93.8 N.A. N.A. N.A. 60.8 N.A. 67
P-Site Identity: 100 100 93.3 100 N.A. 86.6 93.3 N.A. 13.3 N.A. 86.6 N.A. N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 40 N.A. 93.3 N.A. N.A. N.A. 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 70 0 10 10 0 70 0 0 0 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 10 0 0 10 10 0 0 0 0 0 10 20 0 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 20 0 0 10 0 0 10 10 10 0 0 10 0 % K
% Leu: 0 0 0 10 10 0 0 0 30 70 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % M
% Asn: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 10 10 10 0 0 10 0 0 0 10 % P
% Gln: 70 0 0 20 0 0 0 0 0 0 0 70 0 0 0 % Q
% Arg: 10 70 60 70 70 0 0 10 0 0 10 0 70 80 0 % R
% Ser: 0 0 0 0 0 0 70 70 0 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 40 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _