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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EI24 All Species: 22.42
Human Site: S56 Identified Species: 54.81
UniProt: O14681 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14681 NP_001007278.1 340 38965 S56 L A Q R R A Q S I E R K Q E S
Chimpanzee Pan troglodytes XP_001146845 340 38916 S56 L A Q R R A Q S I E R K Q E S
Rhesus Macaque Macaca mulatta XP_001111212 340 38916 S56 L A Q R R A Q S I E R K Q E S
Dog Lupus familis XP_546419 340 38854 S56 L A Q R R A Q S I E R K Q E S
Cat Felis silvestris
Mouse Mus musculus Q61070 340 38914 S56 L A Q R R P Q S V E R K Q E S
Rat Rattus norvegicus Q4KM77 340 38874 S56 L A Q R R A Q S V E R K Q E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519550 392 42815 L93 V P V G R E R L A T E A P L P
Chicken Gallus gallus
Frog Xenopus laevis NP_001088433 340 39103 N56 L A Q R R A Q N E E R K P E N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395483 318 35920 K49 N K T E S H G K D I A V I P H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201462 319 36692 E50 K R E E K M M E A R R R P L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.1 99.1 N.A. 98.2 98.2 N.A. 61.2 N.A. 89.1 N.A. N.A. N.A. 43.8 N.A. 46.7
Protein Similarity: 100 99.7 99.7 99.4 N.A. 99.1 99.4 N.A. 65.5 N.A. 93.8 N.A. N.A. N.A. 60.8 N.A. 67
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 6.6 N.A. 73.3 N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 20 N.A. 86.6 N.A. N.A. N.A. 0 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 0 0 0 60 0 0 20 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 10 20 0 10 0 10 10 70 10 0 0 70 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 40 10 0 0 10 0 0 % I
% Lys: 10 10 0 0 10 0 0 10 0 0 0 70 0 0 0 % K
% Leu: 70 0 0 0 0 0 0 10 0 0 0 0 0 20 0 % L
% Met: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % N
% Pro: 0 10 0 0 0 10 0 0 0 0 0 0 30 10 20 % P
% Gln: 0 0 70 0 0 0 70 0 0 0 0 0 60 0 0 % Q
% Arg: 0 10 0 70 80 0 10 0 0 10 80 10 0 0 0 % R
% Ser: 0 0 0 0 10 0 0 60 0 0 0 0 0 0 60 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 10 0 10 0 0 0 0 0 20 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _