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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EI24
All Species:
32.73
Human Site:
T282
Identified Species:
80
UniProt:
O14681
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14681
NP_001007278.1
340
38965
T282
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Chimpanzee
Pan troglodytes
XP_001146845
340
38916
T282
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Rhesus Macaque
Macaca mulatta
XP_001111212
340
38916
T282
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Dog
Lupus familis
XP_546419
340
38854
T282
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q61070
340
38914
T282
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Rat
Rattus norvegicus
Q4KM77
340
38874
T282
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519550
392
42815
T334
I
S
A
N
E
A
K
T
P
G
K
A
Y
L
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088433
340
39103
T282
I
S
A
N
E
A
K
T
P
V
K
V
Y
H
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395483
318
35920
S261
V
L
T
Q
L
P
S
S
Y
V
I
S
G
C
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201462
319
36692
S262
L
P
K
S
Y
F
V
S
G
C
V
F
S
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
99.1
N.A.
98.2
98.2
N.A.
61.2
N.A.
89.1
N.A.
N.A.
N.A.
43.8
N.A.
46.7
Protein Similarity:
100
99.7
99.7
99.4
N.A.
99.1
99.4
N.A.
65.5
N.A.
93.8
N.A.
N.A.
N.A.
60.8
N.A.
67
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
80
0
0
0
0
0
70
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
80
% F
% Gly:
0
0
0
0
0
0
0
0
10
70
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
80
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
80
0
0
0
80
0
0
0
0
% K
% Leu:
10
10
0
0
10
0
0
0
0
0
0
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
0
0
80
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
80
0
10
0
0
10
20
0
0
0
10
10
0
0
% S
% Thr:
0
0
10
0
0
0
0
80
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
10
0
0
20
10
10
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
10
0
0
0
80
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _