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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENC1
All Species:
36.36
Human Site:
S355
Identified Species:
80
UniProt:
O14682
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14682
NP_003624.1
589
66130
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Chimpanzee
Pan troglodytes
XP_526897
589
66099
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Rhesus Macaque
Macaca mulatta
XP_001086777
589
65843
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Dog
Lupus familis
XP_544373
647
71901
S413
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
O35709
589
66067
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Rat
Rattus norvegicus
Q4KLM4
589
65822
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512217
589
65945
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Chicken
Gallus gallus
XP_424790
589
66071
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Frog
Xenopus laevis
Q6DFF7
589
66062
S355
R
G
S
E
N
G
V
S
K
D
V
W
V
Y
D
Zebra Danio
Brachydanio rerio
Q1LYM6
583
66823
L344
V
G
G
L
S
L
S
L
V
S
G
D
S
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
G375
N
D
L
L
Y
A
V
G
G
H
D
G
Q
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
74.6
90.8
N.A.
99.1
73
N.A.
97.7
96.5
74.8
29.2
N.A.
30.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
90.8
N.A.
99.6
85.9
N.A.
98.6
98.4
86.9
48.7
N.A.
48.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
82
10
10
0
0
82
% D
% Glu:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
91
10
0
0
82
0
10
10
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% K
% Leu:
0
0
10
19
0
10
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
82
0
10
0
10
82
0
10
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
91
0
10
0
82
0
82
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
82
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _