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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENC1
All Species:
34.85
Human Site:
T452
Identified Species:
76.67
UniProt:
O14682
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14682
NP_003624.1
589
66130
T452
K
L
F
A
F
G
G
T
S
V
S
H
D
K
L
Chimpanzee
Pan troglodytes
XP_526897
589
66099
T452
K
L
F
A
F
G
G
T
S
V
S
H
D
K
L
Rhesus Macaque
Macaca mulatta
XP_001086777
589
65843
T452
K
L
F
V
F
G
G
T
S
I
H
R
D
M
V
Dog
Lupus familis
XP_544373
647
71901
T510
K
L
F
A
F
G
G
T
S
V
S
H
D
K
L
Cat
Felis silvestris
Mouse
Mus musculus
O35709
589
66067
T452
K
L
F
A
F
G
G
T
S
V
S
H
D
K
L
Rat
Rattus norvegicus
Q4KLM4
589
65822
T452
K
L
F
V
F
G
G
T
S
I
H
R
D
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512217
589
65945
T452
K
L
F
A
F
G
G
T
S
V
S
H
D
K
L
Chicken
Gallus gallus
XP_424790
589
66071
T452
K
L
F
A
F
G
G
T
S
V
S
H
D
K
L
Frog
Xenopus laevis
Q6DFF7
589
66062
T452
K
L
F
V
F
G
G
T
S
I
H
R
D
R
V
Zebra Danio
Brachydanio rerio
Q1LYM6
583
66823
E441
R
I
Y
V
F
G
G
E
D
A
L
Q
N
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
S472
F
L
Y
A
I
G
G
S
D
G
Q
C
P
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
74.6
90.8
N.A.
99.1
73
N.A.
97.7
96.5
74.8
29.2
N.A.
30.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
90.8
N.A.
99.6
85.9
N.A.
98.6
98.4
86.9
48.7
N.A.
48.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
100
N.A.
100
60
N.A.
100
100
60
20
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
100
73.3
N.A.
100
100
80
53.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
64
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
19
0
0
0
82
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
10
0
82
0
91
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
100
100
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
28
55
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
28
0
0
0
0
0
% I
% Lys:
82
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% K
% Leu:
0
91
0
0
0
0
0
0
0
0
10
0
0
10
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
28
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
10
82
0
55
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% T
% Val:
0
0
0
37
0
0
0
0
0
55
0
0
0
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _