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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENC1 All Species: 33.33
Human Site: T46 Identified Species: 73.33
UniProt: O14682 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14682 NP_003624.1 589 66130 T46 L R Q Q R L F T D V L L H A G
Chimpanzee Pan troglodytes XP_526897 589 66099 T46 L R Q Q R L F T D V L L H A G
Rhesus Macaque Macaca mulatta XP_001086777 589 65843 T46 L R K H C M F T D V T L W A G
Dog Lupus familis XP_544373 647 71901 T104 L R Q Q R L F T D V L L H A G
Cat Felis silvestris
Mouse Mus musculus O35709 589 66067 T46 L R Q Q R L F T D V L L H A G
Rat Rattus norvegicus Q4KLM4 589 65822 T46 L R K H C M F T D V T L W A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512217 589 65945 T46 L R Q Q R L F T D V L L H A G
Chicken Gallus gallus XP_424790 589 66071 T46 L R Q Q R L F T D V L L H A G
Frog Xenopus laevis Q6DFF7 589 66062 T46 M R K Q R L F T D M T L W A G
Zebra Danio Brachydanio rerio Q1LYM6 583 66823 P46 C T E D K E I P C H R N V L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 C72 L R R H R E L C D V V L N V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 74.6 90.8 N.A. 99.1 73 N.A. 97.7 96.5 74.8 29.2 N.A. 30.8 N.A. N.A. N.A.
Protein Similarity: 100 99.8 86.9 90.8 N.A. 99.6 85.9 N.A. 98.6 98.4 86.9 48.7 N.A. 48.4 N.A. N.A. N.A.
P-Site Identity: 100 100 60 100 N.A. 100 60 N.A. 100 100 66.6 0 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 100 N.A. 100 73.3 N.A. 100 100 86.6 13.3 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % A
% Cys: 10 0 0 0 19 0 0 10 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 91 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 19 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % G
% His: 0 0 0 28 0 0 0 0 0 10 0 0 55 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 28 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 82 0 0 0 0 64 10 0 0 0 55 91 0 10 0 % L
% Met: 10 0 0 0 0 19 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 55 64 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 91 10 0 73 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 0 82 0 0 28 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 82 10 0 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _