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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRDMT1 All Species: 29.39
Human Site: S150 Identified Species: 58.79
UniProt: O14717 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14717 NP_004403.1 391 44597 S150 Q Y Q E F L L S P T S L G I P
Chimpanzee Pan troglodytes XP_001151907 391 44604 S150 Q Y Q E F L L S P T S L G I P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848593 391 44814 S150 Q Y Q E F L L S P T S F G I P
Cat Felis silvestris
Mouse Mus musculus O55055 415 46776 S150 Q Y Q E F L L S P S S L G I P
Rat Rattus norvegicus Q4G073 391 44051 S150 Q Y Q E F L L S P S S L G I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520279 343 37945 T117 G D A A D G R T N S F L Y L L
Chicken Gallus gallus NP_001020002 398 45076 S150 K Y Q E F L L S P T C L G I P
Frog Xenopus laevis NP_001079673 382 42977 R147 G I P N S R L R Y F L I A K L
Zebra Danio Brachydanio rerio NP_001018153 381 43910 S153 S F Q E F L I S P T S L G I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036355 345 39358 V119 E Y I L M E N V K G F E S S Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309610 350 39899 T123 E N V V G F E T S D T R A K M
Maize Zea mays NP_001105173 357 40520 T131 V G F E V S D T H D Q L L E V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 86.9 N.A. 76.6 81 N.A. 49.3 67 62.1 60.6 N.A. 36 N.A. N.A. N.A.
Protein Similarity: 100 100 N.A. 93.6 N.A. 83.8 89.5 N.A. 59.3 80.9 75.4 77.2 N.A. 55.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 86.6 6.6 80 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 26.6 93.3 13.3 93.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: 38.1 36.8 N.A. N.A. N.A. N.A.
Protein Similarity: 55.5 56.5 N.A. N.A. N.A. N.A.
P-Site Identity: 0 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 20 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 0 0 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 9 0 0 9 0 9 0 0 17 0 0 0 0 0 % D
% Glu: 17 0 0 67 0 9 9 0 0 0 0 9 0 9 0 % E
% Phe: 0 9 9 0 59 9 0 0 0 9 17 9 0 0 0 % F
% Gly: 17 9 0 0 9 9 0 0 0 9 0 0 59 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 0 0 9 0 0 0 0 9 0 59 0 % I
% Lys: 9 0 0 0 0 0 0 0 9 0 0 0 0 17 0 % K
% Leu: 0 0 0 9 0 59 59 0 0 0 9 67 9 9 17 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 9 0 9 0 0 9 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 59 0 0 0 0 0 59 % P
% Gln: 42 0 59 0 0 0 0 0 0 0 9 0 0 0 9 % Q
% Arg: 0 0 0 0 0 9 9 9 0 0 0 9 0 0 0 % R
% Ser: 9 0 0 0 9 9 0 59 9 25 50 0 9 9 0 % S
% Thr: 0 0 0 0 0 0 0 25 0 42 9 0 0 0 0 % T
% Val: 9 0 9 9 9 0 0 9 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 59 0 0 0 0 0 0 9 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _