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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRDMT1
All Species:
29.39
Human Site:
S306
Identified Species:
58.79
UniProt:
O14717
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14717
NP_004403.1
391
44597
S306
S
Y
I
E
G
T
G
S
V
L
Q
T
A
E
D
Chimpanzee
Pan troglodytes
XP_001151907
391
44604
S306
S
Y
I
E
G
T
G
S
V
L
Q
T
A
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848593
391
44814
S306
S
Y
V
E
G
T
G
S
V
L
Q
T
T
E
D
Cat
Felis silvestris
Mouse
Mus musculus
O55055
415
46776
S306
S
Y
I
E
G
T
G
S
V
L
Q
A
A
E
D
Rat
Rattus norvegicus
Q4G073
391
44051
S306
S
Y
I
E
G
T
G
S
V
L
Q
T
A
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520279
343
37945
E265
F
K
L
E
T
A
E
E
M
Q
R
K
R
Q
R
Chicken
Gallus gallus
NP_001020002
398
45076
S313
H
Y
V
E
G
T
G
S
V
L
Q
T
A
V
D
Frog
Xenopus laevis
NP_001079673
382
42977
S295
H
Y
V
E
G
T
G
S
V
L
Q
T
A
T
D
Zebra Danio
Brachydanio rerio
NP_001018153
381
43910
M301
G
S
V
L
Q
S
C
M
D
V
D
L
E
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036355
345
39358
I267
I
F
E
L
V
K
E
I
D
T
S
N
Q
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309610
350
39899
V272
T
K
S
Y
Y
R
Y
V
K
G
T
G
S
L
L
Maize
Zea mays
NP_001105173
357
40520
S279
R
Y
V
K
G
T
G
S
L
L
A
T
S
K
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
86.9
N.A.
76.6
81
N.A.
49.3
67
62.1
60.6
N.A.
36
N.A.
N.A.
N.A.
Protein Similarity:
100
100
N.A.
93.6
N.A.
83.8
89.5
N.A.
59.3
80.9
75.4
77.2
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
100
N.A.
6.6
80
80
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
100
N.A.
33.3
86.6
86.6
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
38.1
36.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
55.5
56.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
46.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
9
9
50
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
17
0
9
0
0
9
59
% D
% Glu:
0
0
9
67
0
0
17
9
0
0
0
0
9
42
0
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
67
0
67
0
0
9
0
9
0
0
0
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
34
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
9
0
9
0
0
9
0
0
9
0
9
0
% K
% Leu:
0
0
9
17
0
0
0
0
9
67
0
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
59
0
9
9
0
% Q
% Arg:
9
0
0
0
0
9
0
0
0
0
9
0
9
0
9
% R
% Ser:
42
9
9
0
0
9
0
67
0
0
9
0
17
0
0
% S
% Thr:
9
0
0
0
9
67
0
0
0
9
9
59
9
17
0
% T
% Val:
0
0
42
0
9
0
0
9
59
9
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
9
9
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _