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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRDMT1 All Species: 29.39
Human Site: S306 Identified Species: 58.79
UniProt: O14717 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14717 NP_004403.1 391 44597 S306 S Y I E G T G S V L Q T A E D
Chimpanzee Pan troglodytes XP_001151907 391 44604 S306 S Y I E G T G S V L Q T A E D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848593 391 44814 S306 S Y V E G T G S V L Q T T E D
Cat Felis silvestris
Mouse Mus musculus O55055 415 46776 S306 S Y I E G T G S V L Q A A E D
Rat Rattus norvegicus Q4G073 391 44051 S306 S Y I E G T G S V L Q T A E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520279 343 37945 E265 F K L E T A E E M Q R K R Q R
Chicken Gallus gallus NP_001020002 398 45076 S313 H Y V E G T G S V L Q T A V D
Frog Xenopus laevis NP_001079673 382 42977 S295 H Y V E G T G S V L Q T A T D
Zebra Danio Brachydanio rerio NP_001018153 381 43910 M301 G S V L Q S C M D V D L E T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036355 345 39358 I267 I F E L V K E I D T S N Q D A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309610 350 39899 V272 T K S Y Y R Y V K G T G S L L
Maize Zea mays NP_001105173 357 40520 S279 R Y V K G T G S L L A T S K N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 86.9 N.A. 76.6 81 N.A. 49.3 67 62.1 60.6 N.A. 36 N.A. N.A. N.A.
Protein Similarity: 100 100 N.A. 93.6 N.A. 83.8 89.5 N.A. 59.3 80.9 75.4 77.2 N.A. 55.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 100 N.A. 6.6 80 80 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 100 N.A. 33.3 86.6 86.6 20 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: 38.1 36.8 N.A. N.A. N.A. N.A.
Protein Similarity: 55.5 56.5 N.A. N.A. N.A. N.A.
P-Site Identity: 0 46.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 86.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 0 0 0 9 9 50 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 17 0 9 0 0 9 59 % D
% Glu: 0 0 9 67 0 0 17 9 0 0 0 0 9 42 0 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 67 0 67 0 0 9 0 9 0 0 0 % G
% His: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 34 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 17 0 9 0 9 0 0 9 0 0 9 0 9 0 % K
% Leu: 0 0 9 17 0 0 0 0 9 67 0 9 0 9 9 % L
% Met: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 9 59 0 9 9 0 % Q
% Arg: 9 0 0 0 0 9 0 0 0 0 9 0 9 0 9 % R
% Ser: 42 9 9 0 0 9 0 67 0 0 9 0 17 0 0 % S
% Thr: 9 0 0 0 9 67 0 0 0 9 9 59 9 17 0 % T
% Val: 0 0 42 0 9 0 0 9 59 9 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 67 0 9 9 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _