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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRDMT1
All Species:
11.82
Human Site:
Y197
Identified Species:
23.64
UniProt:
O14717
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14717
NP_004403.1
391
44597
Y197
E
S
V
H
P
Q
K
Y
A
M
D
V
E
N
K
Chimpanzee
Pan troglodytes
XP_001151907
391
44604
Y197
E
S
V
H
P
Q
K
Y
A
M
D
V
E
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848593
391
44814
N197
E
S
E
N
P
E
K
N
T
I
D
A
E
N
K
Cat
Felis silvestris
Mouse
Mus musculus
O55055
415
46776
Y197
V
T
V
E
P
Q
K
Y
A
V
V
E
E
S
Q
Rat
Rattus norvegicus
Q4G073
391
44051
Y197
G
T
V
Q
P
Q
E
Y
A
V
V
E
E
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520279
343
37945
E159
D
L
L
V
Q
T
I
E
K
C
G
F
Q
Y
Q
Chicken
Gallus gallus
NP_001020002
398
45076
G204
D
K
V
V
D
K
T
G
S
X
F
P
S
G
E
Frog
Xenopus laevis
NP_001079673
382
42977
E189
R
R
V
I
H
C
S
E
N
N
P
Q
A
G
A
Zebra Danio
Brachydanio rerio
NP_001018153
381
43910
T195
G
F
P
M
S
E
S
T
D
G
L
S
V
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036355
345
39358
Y161
V
P
N
T
R
Y
R
Y
Y
C
I
A
R
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309610
350
39899
R166
R
Y
F
C
L
A
K
R
K
P
L
S
F
H
H
Maize
Zea mays
NP_001105173
357
40520
P173
F
C
L
A
K
R
E
P
V
R
F
R
H
A
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
86.9
N.A.
76.6
81
N.A.
49.3
67
62.1
60.6
N.A.
36
N.A.
N.A.
N.A.
Protein Similarity:
100
100
N.A.
93.6
N.A.
83.8
89.5
N.A.
59.3
80.9
75.4
77.2
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
53.3
N.A.
46.6
46.6
N.A.
0
6.6
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
73.3
N.A.
73.3
66.6
N.A.
26.6
33.3
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
38.1
36.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
55.5
56.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
34
0
0
17
9
9
9
% A
% Cys:
0
9
0
9
0
9
0
0
0
17
0
0
0
0
0
% C
% Asp:
17
0
0
0
9
0
0
0
9
0
25
0
0
0
0
% D
% Glu:
25
0
9
9
0
17
17
17
0
0
0
17
42
0
9
% E
% Phe:
9
9
9
0
0
0
0
0
0
0
17
9
9
0
9
% F
% Gly:
17
0
0
0
0
0
0
9
0
9
9
0
0
25
9
% G
% His:
0
0
0
17
9
0
0
0
0
0
0
0
9
9
9
% H
% Ile:
0
0
0
9
0
0
9
0
0
9
9
0
0
0
0
% I
% Lys:
0
9
0
0
9
9
42
0
17
0
0
0
0
9
34
% K
% Leu:
0
9
17
0
9
0
0
0
0
0
17
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
9
9
9
0
0
0
25
0
% N
% Pro:
0
9
9
0
42
0
0
9
0
9
9
9
0
9
0
% P
% Gln:
0
0
0
9
9
34
0
0
0
0
0
9
9
0
17
% Q
% Arg:
17
9
0
0
9
9
9
9
0
9
0
9
9
0
0
% R
% Ser:
0
25
0
0
9
0
17
0
9
0
0
17
9
9
0
% S
% Thr:
0
17
0
9
0
9
9
9
9
0
0
0
0
0
0
% T
% Val:
17
0
50
17
0
0
0
0
9
17
17
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
42
9
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _