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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRDMT1
All Species:
26.36
Human Site:
Y266
Identified Species:
52.73
UniProt:
O14717
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14717
NP_004403.1
391
44597
Y266
D
D
T
D
V
N
Q
Y
L
L
P
P
K
S
L
Chimpanzee
Pan troglodytes
XP_001151907
391
44604
Y266
D
D
T
D
V
N
Q
Y
L
L
P
P
K
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848593
391
44814
Y266
D
D
V
D
M
N
Q
Y
F
L
P
P
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O55055
415
46776
Y266
E
D
G
D
T
D
E
Y
L
L
P
P
K
L
L
Rat
Rattus norvegicus
Q4G073
391
44051
Y266
E
D
G
D
T
A
Q
Y
L
L
P
A
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520279
343
37945
G225
R
E
V
A
V
A
G
G
S
E
R
A
A
E
P
Chicken
Gallus gallus
NP_001020002
398
45076
Y273
E
N
E
E
M
S
Q
Y
F
L
A
P
K
S
L
Frog
Xenopus laevis
NP_001079673
382
42977
Y255
S
V
E
E
M
S
Q
Y
F
L
P
P
K
S
L
Zebra Danio
Brachydanio rerio
NP_001018153
381
43910
T261
P
Y
L
L
P
P
K
T
L
L
R
Y
A
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036355
345
39358
A227
V
M
D
I
I
H
P
A
Q
S
R
S
M
C
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309610
350
39899
G232
S
S
N
R
V
T
G
G
T
G
T
D
Y
I
V
Maize
Zea mays
NP_001105173
357
40520
Y239
D
E
T
V
L
Q
D
Y
M
V
P
V
N
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
86.9
N.A.
76.6
81
N.A.
49.3
67
62.1
60.6
N.A.
36
N.A.
N.A.
N.A.
Protein Similarity:
100
100
N.A.
93.6
N.A.
83.8
89.5
N.A.
59.3
80.9
75.4
77.2
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
60
66.6
N.A.
6.6
46.6
53.3
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
80
73.3
N.A.
13.3
80
73.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
38.1
36.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
55.5
56.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
17
0
9
0
0
9
17
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
34
42
9
42
0
9
9
0
0
0
0
9
0
0
0
% D
% Glu:
25
17
17
17
0
0
9
0
0
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
9
% F
% Gly:
0
0
17
0
0
0
17
17
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
59
0
0
% K
% Leu:
0
0
9
9
9
0
0
0
42
67
0
0
0
25
59
% L
% Met:
0
9
0
0
25
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
9
9
0
0
25
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
0
0
0
9
9
9
0
0
0
59
50
0
0
9
% P
% Gln:
0
0
0
0
0
9
50
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
0
25
0
0
0
0
% R
% Ser:
17
9
0
0
0
17
0
0
9
9
0
9
0
50
0
% S
% Thr:
0
0
25
0
17
9
0
9
9
0
9
0
0
0
0
% T
% Val:
9
9
17
9
34
0
0
0
0
9
0
9
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
67
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _