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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APAF1 All Species: 0
Human Site: S102 Identified Species: 0
UniProt: O14727 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14727 NP_001151.1 1248 141840 S102 S S S S G K D S V S G I T S Y
Chimpanzee Pan troglodytes XP_509290 1248 141889
Rhesus Macaque Macaca mulatta XP_001087067 1248 142132
Dog Lupus familis XP_539737 1250 142155
Cat Felis silvestris
Mouse Mus musculus O88879 1249 140870
Rat Rattus norvegicus Q9EPV5 1249 141134
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505891 1250 142195
Chicken Gallus gallus XP_416167 1243 141542
Frog Xenopus laevis NP_001085834 1248 141557
Zebra Danio Brachydanio rerio Q9I9H8 1261 142916
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199578 1250 139666
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.2 90.8 N.A. 87.5 87.3 N.A. 81.1 69.7 60.7 54.8 N.A. N.A. N.A. N.A. 34.4
Protein Similarity: 100 99.8 98.4 94.9 N.A. 93.8 93.9 N.A. 89.6 82.3 76.8 74 N.A. N.A. N.A. N.A. 54.8
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 100 0 0 0 0 0 100 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % I
% Lys: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 100 100 100 100 0 0 0 100 0 100 0 0 0 100 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % T
% Val: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _