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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK3
All Species:
24.85
Human Site:
S125
Identified Species:
45.56
UniProt:
O14730
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14730
NP_003822.2
519
59093
S125
K
V
H
P
Y
E
D
S
D
S
S
E
D
E
V
Chimpanzee
Pan troglodytes
XP_523888
519
59089
S125
K
V
H
P
Y
E
D
S
D
S
S
E
D
E
V
Rhesus Macaque
Macaca mulatta
XP_001093347
272
30375
Dog
Lupus familis
XP_537298
519
58851
S125
K
V
H
P
Y
E
D
S
D
S
S
E
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU3
519
58672
S125
K
V
H
P
F
E
D
S
D
S
S
E
D
E
V
Rat
Rattus norvegicus
NP_001101893
519
58785
S125
K
V
H
P
F
E
D
S
D
S
S
E
D
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512693
499
56573
E112
D
S
D
S
S
E
D
E
V
D
W
Q
D
T
S
Chicken
Gallus gallus
XP_419160
517
58611
D128
K
V
H
P
F
D
S
D
S
S
E
D
E
V
D
Frog
Xenopus laevis
NP_001087045
508
58067
N119
K
V
H
P
S
E
E
N
D
S
S
E
D
E
V
Zebra Danio
Brachydanio rerio
NP_001003614
507
57910
S117
M
V
H
P
Y
E
D
S
D
S
S
E
D
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608871
603
69260
L146
R
D
G
D
A
E
F
L
H
D
T
A
E
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34649
510
58547
S122
K
T
M
Q
E
T
D
S
E
N
E
D
D
D
A
Sea Urchin
Strong. purpuratus
XP_794489
324
37399
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
52
96.3
N.A.
93.8
94
N.A.
85.1
86.9
76.1
71.2
N.A.
37.4
N.A.
32.9
39.5
Protein Similarity:
100
100
52.2
97.8
N.A.
97.5
97.6
N.A.
89.9
91.5
85.5
81.3
N.A.
53.4
N.A.
53.5
49.1
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
20
33.3
80
93.3
N.A.
6.6
N.A.
26.6
0
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
26.6
60
93.3
93.3
N.A.
33.3
N.A.
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
8
62
8
54
16
0
16
70
16
16
% D
% Glu:
0
0
0
0
8
70
8
8
8
0
16
54
16
54
0
% E
% Phe:
0
0
0
0
24
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
62
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
16
0
8
54
8
62
54
0
0
0
8
% S
% Thr:
0
8
0
0
0
8
0
0
0
0
8
0
0
8
0
% T
% Val:
0
62
0
0
0
0
0
0
8
0
0
0
0
8
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _