KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK3
All Species:
35.76
Human Site:
S217
Identified Species:
65.56
UniProt:
O14730
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14730
NP_003822.2
519
59093
S217
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Chimpanzee
Pan troglodytes
XP_523888
519
59089
S217
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Rhesus Macaque
Macaca mulatta
XP_001093347
272
30375
S8
M
D
L
V
G
V
A
S
P
E
P
G
P
A
A
Dog
Lupus familis
XP_537298
519
58851
S217
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU3
519
58672
S217
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Rat
Rattus norvegicus
NP_001101893
519
58785
S217
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512693
499
56573
S198
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Chicken
Gallus gallus
XP_419160
517
58611
S219
A
Y
S
E
E
R
R
S
A
R
L
H
E
K
K
Frog
Xenopus laevis
NP_001087045
508
58067
S211
S
I
S
E
Q
R
K
S
A
R
L
H
D
K
K
Zebra Danio
Brachydanio rerio
NP_001003614
507
57910
S209
C
Q
T
E
Q
R
R
S
A
R
L
H
E
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608871
603
69260
A252
S
D
K
H
E
K
V
A
T
A
E
M
G
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34649
510
58547
Q213
G
K
S
E
S
K
R
Q
M
R
N
K
D
K
E
Sea Urchin
Strong. purpuratus
XP_794489
324
37399
N60
V
H
P
A
Y
D
D
N
E
D
D
D
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
52
96.3
N.A.
93.8
94
N.A.
85.1
86.9
76.1
71.2
N.A.
37.4
N.A.
32.9
39.5
Protein Similarity:
100
100
52.2
97.8
N.A.
97.5
97.6
N.A.
89.9
91.5
85.5
81.3
N.A.
53.4
N.A.
53.5
49.1
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
66.6
73.3
N.A.
6.6
N.A.
33.3
0
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
26.6
N.A.
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
8
0
0
8
8
70
8
0
0
0
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
8
8
0
0
8
8
8
24
8
16
% D
% Glu:
0
0
0
77
62
0
0
0
8
8
8
0
62
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
70
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
16
8
0
0
0
0
8
0
77
70
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
70
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
8
0
0
16
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
70
70
0
0
77
0
0
0
0
0
% R
% Ser:
16
0
70
0
8
0
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
54
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _