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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK3
All Species:
9.09
Human Site:
S280
Identified Species:
16.67
UniProt:
O14730
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14730
NP_003822.2
519
59093
S280
M
E
D
E
K
E
D
S
K
V
I
P
T
E
C
Chimpanzee
Pan troglodytes
XP_523888
519
59089
S280
M
E
D
E
K
E
D
S
K
V
I
P
T
E
C
Rhesus Macaque
Macaca mulatta
XP_001093347
272
30375
N71
G
P
F
I
T
G
E
N
I
D
T
S
S
D
L
Dog
Lupus familis
XP_537298
519
58851
S280
M
E
D
E
K
E
D
S
K
V
I
P
T
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU3
519
58672
G280
L
E
D
E
K
E
D
G
K
A
I
P
T
E
C
Rat
Rattus norvegicus
NP_001101893
519
58785
G280
L
E
D
E
K
E
D
G
K
V
I
P
T
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512693
499
56573
Q261
L
E
E
K
G
E
G
Q
G
V
P
A
E
C
A
Chicken
Gallus gallus
XP_419160
517
58611
V282
S
A
T
E
E
D
K
V
I
P
P
E
C
A
I
Frog
Xenopus laevis
NP_001087045
508
58067
A274
M
E
D
Q
E
I
P
A
E
C
A
L
K
V
F
Zebra Danio
Brachydanio rerio
NP_001003614
507
57910
E272
F
E
E
M
I
V
P
E
E
C
V
L
K
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608871
603
69260
P315
Q
S
G
V
L
V
P
P
Q
L
L
P
R
E
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34649
510
58547
V276
A
T
S
Y
A
I
K
V
Y
K
T
T
L
S
E
Sea Urchin
Strong. purpuratus
XP_794489
324
37399
A123
V
M
N
Q
F
P
P
A
F
P
T
G
N
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
52
96.3
N.A.
93.8
94
N.A.
85.1
86.9
76.1
71.2
N.A.
37.4
N.A.
32.9
39.5
Protein Similarity:
100
100
52.2
97.8
N.A.
97.5
97.6
N.A.
89.9
91.5
85.5
81.3
N.A.
53.4
N.A.
53.5
49.1
P-Site Identity:
100
100
0
100
N.A.
80
86.6
N.A.
20
6.6
20
6.6
N.A.
20
N.A.
0
0
P-Site Similarity:
100
100
26.6
100
N.A.
86.6
93.3
N.A.
40
20
46.6
26.6
N.A.
40
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
16
0
8
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
8
8
47
% C
% Asp:
0
0
47
0
0
8
39
0
0
8
0
0
0
8
0
% D
% Glu:
0
62
16
47
16
47
8
8
16
0
0
8
8
47
8
% E
% Phe:
8
0
8
0
8
0
0
0
8
0
0
0
0
0
24
% F
% Gly:
8
0
8
0
8
8
8
16
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
16
0
0
16
0
39
0
0
0
8
% I
% Lys:
0
0
0
8
39
0
16
0
39
8
0
0
16
0
0
% K
% Leu:
24
0
0
0
8
0
0
0
0
8
8
16
8
0
8
% L
% Met:
31
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
8
31
8
0
16
16
47
0
0
0
% P
% Gln:
8
0
0
16
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
8
8
0
0
0
0
24
0
0
0
8
8
16
0
% S
% Thr:
0
8
8
0
8
0
0
0
0
0
24
8
39
0
0
% T
% Val:
8
0
0
8
0
16
0
16
0
39
8
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _