KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK3
All Species:
18.18
Human Site:
S379
Identified Species:
33.33
UniProt:
O14730
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14730
NP_003822.2
519
59093
S379
L
K
E
V
K
L
N
S
E
E
M
K
E
A
Y
Chimpanzee
Pan troglodytes
XP_523888
519
59089
S379
L
K
E
V
K
L
N
S
E
E
M
K
E
A
Y
Rhesus Macaque
Macaca mulatta
XP_001093347
272
30375
T150
R
P
A
K
P
V
P
T
P
K
K
G
F
I
G
Dog
Lupus familis
XP_537298
519
58851
S379
L
K
E
V
K
L
S
S
E
E
M
K
E
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU3
519
58672
N379
L
K
E
V
K
L
S
N
E
E
M
K
D
A
Y
Rat
Rattus norvegicus
NP_001101893
519
58785
E379
L
K
E
V
K
L
S
E
E
E
M
K
D
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512693
499
56573
G359
L
K
E
V
K
L
G
G
E
D
M
K
Q
A
Y
Chicken
Gallus gallus
XP_419160
517
58611
S379
L
K
D
V
K
L
N
S
E
D
M
K
K
A
Y
Frog
Xenopus laevis
NP_001087045
508
58067
L368
L
K
E
A
K
L
G
L
E
E
S
K
Q
A
Y
Zebra Danio
Brachydanio rerio
NP_001003614
507
57910
S366
L
K
D
A
I
L
N
S
E
D
M
K
N
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608871
603
69260
D414
L
K
D
A
R
L
S
D
A
E
L
S
C
A
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34649
510
58547
D361
V
E
W
E
F
F
T
D
D
E
R
R
N
V
Y
Sea Urchin
Strong. purpuratus
XP_794489
324
37399
V202
I
S
T
G
K
E
A
V
V
I
H
A
Y
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
52
96.3
N.A.
93.8
94
N.A.
85.1
86.9
76.1
71.2
N.A.
37.4
N.A.
32.9
39.5
Protein Similarity:
100
100
52.2
97.8
N.A.
97.5
97.6
N.A.
89.9
91.5
85.5
81.3
N.A.
53.4
N.A.
53.5
49.1
P-Site Identity:
100
100
0
93.3
N.A.
80
80
N.A.
73.3
80
66.6
66.6
N.A.
40
N.A.
13.3
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
93.3
N.A.
86.6
100
73.3
80
N.A.
66.6
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
24
0
0
8
0
8
0
0
8
0
77
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
24
0
0
0
0
16
8
24
0
0
16
0
0
% D
% Glu:
0
8
54
8
0
8
0
8
70
62
0
0
24
0
0
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
16
8
0
0
0
8
0
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
77
0
8
70
0
0
0
0
8
8
70
8
0
0
% K
% Leu:
77
0
0
0
0
77
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
31
8
0
0
0
0
16
0
0
% N
% Pro:
0
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% R
% Ser:
0
8
0
0
0
0
31
39
0
0
8
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
54
0
8
0
8
8
0
0
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
85
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _