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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK3
All Species:
27.27
Human Site:
S505
Identified Species:
50
UniProt:
O14730
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14730
NP_003822.2
519
59093
S505
K
N
G
R
K
A
A
S
F
L
K
D
D
G
D
Chimpanzee
Pan troglodytes
XP_523888
519
59089
S505
K
N
G
R
K
A
A
S
F
L
K
D
D
G
D
Rhesus Macaque
Macaca mulatta
XP_001093347
272
30375
T259
T
I
T
G
C
I
S
T
G
K
E
S
V
V
F
Dog
Lupus familis
XP_537298
519
58851
S505
K
N
G
R
K
A
A
S
F
L
K
D
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU3
519
58672
S505
K
N
G
R
K
A
A
S
F
L
K
D
D
G
S
Rat
Rattus norvegicus
NP_001101893
519
58785
S505
K
N
G
R
K
A
A
S
F
L
K
D
E
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512693
499
56573
S485
K
N
G
R
K
A
A
S
F
Q
R
D
D
G
G
Chicken
Gallus gallus
XP_419160
517
58611
S504
Q
N
H
G
K
K
V
S
T
F
S
T
D
G
D
Frog
Xenopus laevis
NP_001087045
508
58067
L494
M
H
G
K
K
V
S
L
Y
Q
K
D
D
D
G
Zebra Danio
Brachydanio rerio
NP_001003614
507
57910
S492
K
S
G
K
K
I
F
S
D
T
Y
E
G
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608871
603
69260
Q566
R
A
A
Q
K
A
L
Q
Q
A
Q
D
N
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34649
510
58547
V476
F
S
E
E
N
R
S
V
D
L
R
H
D
K
S
Sea Urchin
Strong. purpuratus
XP_794489
324
37399
S311
K
L
K
H
V
K
F
S
V
S
E
A
Q
C
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
52
96.3
N.A.
93.8
94
N.A.
85.1
86.9
76.1
71.2
N.A.
37.4
N.A.
32.9
39.5
Protein Similarity:
100
100
52.2
97.8
N.A.
97.5
97.6
N.A.
89.9
91.5
85.5
81.3
N.A.
53.4
N.A.
53.5
49.1
P-Site Identity:
100
100
0
93.3
N.A.
93.3
86.6
N.A.
80
40
33.3
26.6
N.A.
26.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
86.6
46.6
60
46.6
N.A.
53.3
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
54
47
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
16
0
0
62
62
8
31
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
16
8
8
0
0
% E
% Phe:
8
0
0
0
0
0
16
0
47
8
0
0
0
0
8
% F
% Gly:
0
0
62
16
0
0
0
0
8
0
0
0
8
54
24
% G
% His:
0
8
8
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
16
0
0
0
0
0
0
0
0
0
% I
% Lys:
62
0
8
16
77
16
0
0
0
8
47
0
0
8
0
% K
% Leu:
0
8
0
0
0
0
8
8
0
47
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
54
0
0
8
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
8
0
0
0
8
8
16
8
0
8
0
0
% Q
% Arg:
8
0
0
47
0
8
0
0
0
0
16
0
0
0
0
% R
% Ser:
0
16
0
0
0
0
24
70
0
8
8
8
0
8
24
% S
% Thr:
8
0
8
0
0
0
0
8
8
8
0
8
0
0
0
% T
% Val:
0
0
0
0
8
8
8
8
8
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _