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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK3
All Species:
36.06
Human Site:
Y242
Identified Species:
66.11
UniProt:
O14730
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14730
NP_003822.2
519
59093
Y242
P
K
T
R
L
L
M
Y
K
M
V
N
S
G
M
Chimpanzee
Pan troglodytes
XP_523888
519
59089
Y242
P
K
T
R
L
L
M
Y
K
M
V
N
S
G
M
Rhesus Macaque
Macaca mulatta
XP_001093347
272
30375
C33
I
P
Q
N
T
I
S
C
S
L
A
D
V
M
S
Dog
Lupus familis
XP_537298
519
58851
Y242
P
K
T
R
L
L
M
Y
K
M
V
N
S
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU3
519
58672
Y242
P
K
T
R
L
L
M
Y
K
M
V
N
S
G
M
Rat
Rattus norvegicus
NP_001101893
519
58785
Y242
P
K
T
R
L
L
M
Y
K
M
V
N
S
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512693
499
56573
Y223
P
K
T
R
L
L
M
Y
K
M
V
N
S
G
L
Chicken
Gallus gallus
XP_419160
517
58611
Y244
P
K
T
R
L
L
L
Y
K
M
V
S
G
G
M
Frog
Xenopus laevis
NP_001087045
508
58067
Y236
P
K
T
R
L
L
L
Y
K
M
V
N
S
G
V
Zebra Danio
Brachydanio rerio
NP_001003614
507
57910
Y234
P
K
T
R
L
L
M
Y
K
M
V
N
A
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608871
603
69260
Q277
I
N
N
Q
I
L
E
Q
I
N
G
I
I
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34649
510
58547
L238
S
D
T
R
L
L
L
L
K
W
I
N
Q
G
V
Sea Urchin
Strong. purpuratus
XP_794489
324
37399
L85
D
E
G
R
E
A
E
L
L
A
P
P
S
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
52
96.3
N.A.
93.8
94
N.A.
85.1
86.9
76.1
71.2
N.A.
37.4
N.A.
32.9
39.5
Protein Similarity:
100
100
52.2
97.8
N.A.
97.5
97.6
N.A.
89.9
91.5
85.5
81.3
N.A.
53.4
N.A.
53.5
49.1
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
93.3
80
86.6
86.6
N.A.
6.6
N.A.
46.6
13.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
93.3
100
100
N.A.
20
N.A.
66.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
0
8
0
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
8
77
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
8
8
0
0
8
0
8
8
8
0
8
% I
% Lys:
0
70
0
0
0
0
0
0
77
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
77
85
24
16
8
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
54
0
0
70
0
0
0
8
47
% M
% Asn:
0
8
8
8
0
0
0
0
0
8
0
70
0
0
0
% N
% Pro:
70
8
0
0
0
0
0
0
0
0
8
8
0
8
0
% P
% Gln:
0
0
8
8
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
8
0
0
8
62
8
16
% S
% Thr:
0
0
77
0
8
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
70
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _