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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMPA2 All Species: 37.27
Human Site: T46 Identified Species: 54.67
UniProt: O14732 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14732 NP_055029.1 288 31321 T46 T E E K R V S T K T S A A D L
Chimpanzee Pan troglodytes XP_512020 288 31286 T46 T E E K R V S T K T S A A D L
Rhesus Macaque Macaca mulatta XP_001096318 288 31313 T46 T E E K R V S T K T S A A D L
Dog Lupus familis XP_851029 410 44016 T168 S E E K R V S T K T S A A D L
Cat Felis silvestris
Mouse Mus musculus Q91UZ5 290 31698 T48 T E E K R V S T K T S A A D L
Rat Rattus norvegicus Q8CIN7 290 31778 T48 T E E K H V S T K T S A A D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508686 235 25995
Chicken Gallus gallus XP_419118 292 31862 T50 T E E K Q V S T K T S A A D L
Frog Xenopus laevis P29219 285 30711 T38 D V S I M V K T S L A P A D L
Zebra Danio Brachydanio rerio NP_001018408 275 29860 S34 Q L E K R V S S K S T P T D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649294 278 30607 K38 Q R Q D F V C K S N D I D L V
Honey Bee Apis mellifera XP_393191 272 29815 T34 N Q P K D A M T K S C E V D L
Nematode Worm Caenorhab. elegans Q19420 285 30962 T41 S P E S K V D T K S S N T D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M8S8 271 29103 R26 K K A G Q I I R K G F Y E T K
Baker's Yeast Sacchar. cerevisiae P38710 295 32805 K37 T Q K D Y D L K T G S R S V D
Red Bread Mold Neurospora crassa P11634 340 37305 V60 F T E K D S A V D I V T Q T D
Conservation
Percent
Protein Identity: 100 99.6 99.3 64.1 N.A. 90.3 89.6 N.A. 72.2 82.8 54.5 66.3 N.A. 42.7 42 38.5 N.A.
Protein Similarity: 100 99.6 99.6 68 N.A. 95.1 94.8 N.A. 76 91 76 78.8 N.A. 61.8 63.5 58.3 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 0 93.3 33.3 53.3 N.A. 6.6 33.3 46.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 0 100 40 73.3 N.A. 20 46.6 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 41.6 31.1 30.5
Protein Similarity: N.A. N.A. N.A. 60 50.5 45.8
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 7 7 0 0 0 7 44 50 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % C
% Asp: 7 0 0 13 13 7 7 0 7 0 7 0 7 69 13 % D
% Glu: 0 44 63 0 0 0 0 0 0 0 0 7 7 0 0 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 13 0 0 0 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 7 0 0 7 0 7 0 0 0 % I
% Lys: 7 7 7 63 7 0 7 13 69 0 0 0 0 0 7 % K
% Leu: 0 7 0 0 0 0 7 0 0 7 0 0 0 7 69 % L
% Met: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % N
% Pro: 0 7 7 0 0 0 0 0 0 0 0 13 0 0 0 % P
% Gln: 13 13 7 0 13 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 7 0 0 38 0 0 7 0 0 0 7 0 0 0 % R
% Ser: 13 0 7 7 0 7 50 7 13 19 57 0 7 0 0 % S
% Thr: 44 7 0 0 0 0 0 63 7 44 7 7 13 13 0 % T
% Val: 0 7 0 0 0 69 0 7 0 0 7 0 7 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _