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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K7
All Species:
18.18
Human Site:
S128
Identified Species:
30.77
UniProt:
O14733
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14733
NP_660186.1
419
47485
S128
E
N
L
G
E
M
G
S
G
T
C
G
Q
V
W
Chimpanzee
Pan troglodytes
XP_001146898
522
57631
S224
E
N
L
G
E
M
G
S
G
T
C
G
Q
V
W
Rhesus Macaque
Macaca mulatta
XP_001098659
367
41194
L93
R
P
R
H
M
L
G
L
P
S
T
L
F
T
P
Dog
Lupus familis
XP_868281
419
47531
S128
E
N
L
G
E
M
G
S
G
T
C
G
Q
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE90
535
59294
S144
E
N
L
G
E
M
G
S
G
T
C
G
Q
V
W
Rat
Rattus norvegicus
Q4KSH7
419
47517
S128
E
N
L
G
E
M
G
S
G
T
C
G
Q
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q07192
446
50082
R157
K
D
L
G
E
I
G
R
G
A
Y
G
S
V
N
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
G87
L
E
Q
I
G
E
L
G
R
G
A
Y
G
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23977
1178
125089
N205
K
H
L
G
D
L
G
N
G
T
S
G
N
V
V
Honey Bee
Apis mellifera
XP_396834
762
86143
H119
G
H
V
V
K
M
R
H
K
P
S
G
V
L
I
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
G89
K
M
R
H
K
E
T
G
K
L
I
A
V
K
R
Sea Urchin
Strong. purpuratus
XP_795810
281
31449
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A06
354
39192
G80
V
I
G
K
G
S
S
G
N
V
Q
L
V
K
H
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
H368
E
F
L
D
E
L
G
H
G
N
Y
G
N
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
83.5
99
N.A.
77.1
99
N.A.
N.A.
N.A.
40.3
39.3
N.A.
22.4
35.2
34.8
43.6
Protein Similarity:
100
78.1
83.7
99.5
N.A.
77.5
99.5
N.A.
N.A.
N.A.
54.4
56.7
N.A.
27.5
43.3
52
54.4
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
N.A.
46.6
6.6
N.A.
46.6
13.3
0
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
N.A.
66.6
6.6
N.A.
80
40
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
36
0
0
0
0
% C
% Asp:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
43
8
0
0
50
15
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
50
15
0
65
22
58
8
0
65
8
0
0
% G
% His:
0
15
0
15
0
0
0
15
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
8
0
8
0
0
0
0
8
0
0
0
8
% I
% Lys:
22
0
0
8
15
0
0
0
15
0
0
0
0
15
0
% K
% Leu:
8
0
58
0
0
22
8
8
0
8
0
15
0
8
0
% L
% Met:
0
8
0
0
8
43
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
36
0
0
0
0
0
8
8
8
0
0
15
0
8
% N
% Pro:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
0
36
0
0
% Q
% Arg:
8
0
15
0
0
0
8
8
8
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
8
8
36
0
8
15
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
43
8
0
0
8
0
% T
% Val:
8
0
8
8
0
0
0
0
0
8
0
0
22
65
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
15
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _