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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K7
All Species:
20.91
Human Site:
S53
Identified Species:
35.38
UniProt:
O14733
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14733
NP_660186.1
419
47485
S53
P
L
A
N
D
G
G
S
R
S
P
S
S
E
S
Chimpanzee
Pan troglodytes
XP_001146898
522
57631
S149
P
L
A
N
D
G
G
S
R
S
P
S
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001098659
367
41194
K18
S
R
L
E
A
K
L
K
Q
E
N
R
E
A
R
Dog
Lupus familis
XP_868281
419
47531
S53
P
L
A
N
D
G
G
S
R
S
P
S
S
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE90
535
59294
S69
P
L
A
N
D
G
G
S
R
S
P
S
S
E
S
Rat
Rattus norvegicus
Q4KSH7
419
47517
S53
P
L
A
N
D
G
G
S
R
S
P
S
S
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q07192
446
50082
V82
P
T
I
Q
S
T
H
V
M
H
K
L
D
A
I
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
F12
S
D
K
E
S
K
V
F
C
D
S
P
S
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23977
1178
125089
V130
Y
T
P
P
T
T
R
V
S
R
A
T
P
T
L
Honey Bee
Apis mellifera
XP_396834
762
86143
G44
S
L
Q
S
S
S
S
G
S
V
S
S
S
A
S
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
S14
E
N
L
R
N
S
M
S
L
R
P
T
S
L
S
Sea Urchin
Strong. purpuratus
XP_795810
281
31449
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A06
354
39192
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
T293
S
T
E
G
P
H
D
T
V
G
T
T
P
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
83.5
99
N.A.
77.1
99
N.A.
N.A.
N.A.
40.3
39.3
N.A.
22.4
35.2
34.8
43.6
Protein Similarity:
100
78.1
83.7
99.5
N.A.
77.5
99.5
N.A.
N.A.
N.A.
54.4
56.7
N.A.
27.5
43.3
52
54.4
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
N.A.
N.A.
6.6
6.6
N.A.
0
26.6
26.6
0
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
N.A.
6.6
13.3
N.A.
6.6
33.3
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
0
8
0
0
0
0
0
8
0
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
36
0
8
0
0
8
0
0
8
0
0
% D
% Glu:
8
0
8
15
0
0
0
0
0
8
0
0
8
36
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
36
36
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
15
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
43
15
0
0
0
8
0
8
0
0
8
0
8
8
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
36
8
0
0
0
0
0
8
0
0
0
15
% N
% Pro:
43
0
8
8
8
0
0
0
0
0
43
8
15
8
0
% P
% Gln:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
8
0
36
15
0
8
0
8
8
% R
% Ser:
29
0
0
8
22
15
8
43
15
36
15
43
58
0
43
% S
% Thr:
0
22
0
0
8
15
0
8
0
0
8
22
0
8
8
% T
% Val:
0
0
0
0
0
0
8
15
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _