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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K7
All Species:
27.27
Human Site:
T362
Identified Species:
46.15
UniProt:
O14733
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14733
NP_660186.1
419
47485
T362
S
F
V
K
D
C
L
T
K
D
H
R
K
R
P
Chimpanzee
Pan troglodytes
XP_001146898
522
57631
T465
S
F
V
K
D
C
L
T
K
D
H
R
K
R
P
Rhesus Macaque
Macaca mulatta
XP_001098659
367
41194
K311
F
V
K
D
C
L
T
K
D
H
R
K
R
P
K
Dog
Lupus familis
XP_868281
419
47531
T362
S
F
V
K
D
C
L
T
K
D
H
R
K
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE90
535
59294
T378
S
F
V
K
D
C
L
T
K
D
H
R
K
R
P
Rat
Rattus norvegicus
Q4KSH7
419
47517
T362
S
F
V
K
D
C
L
T
K
D
H
R
K
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q07192
446
50082
F390
F
S
P
S
F
T
S
F
V
N
Q
C
L
T
K
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
L305
V
E
E
P
S
P
Q
L
P
A
D
R
F
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23977
1178
125089
T438
D
F
V
I
K
C
L
T
K
N
H
Q
D
R
P
Honey Bee
Apis mellifera
XP_396834
762
86143
T342
N
F
V
S
C
C
L
T
K
N
Y
K
H
R
P
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
I307
S
L
P
L
V
K
F
I
N
T
C
L
T
K
D
Sea Urchin
Strong. purpuratus
XP_795810
281
31449
S225
I
S
G
R
L
V
D
S
K
A
R
T
R
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A06
354
39192
S298
C
A
P
S
N
L
F
S
P
E
F
C
S
F
I
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
Q605
D
F
V
S
L
C
L
Q
K
I
P
E
R
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
83.5
99
N.A.
77.1
99
N.A.
N.A.
N.A.
40.3
39.3
N.A.
22.4
35.2
34.8
43.6
Protein Similarity:
100
78.1
83.7
99.5
N.A.
77.5
99.5
N.A.
N.A.
N.A.
54.4
56.7
N.A.
27.5
43.3
52
54.4
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
N.A.
0
6.6
N.A.
60
53.3
6.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
N.A.
6.6
6.6
N.A.
73.3
80
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
15
0
0
0
0
15
% A
% Cys:
8
0
0
0
15
58
0
0
0
0
8
15
0
0
0
% C
% Asp:
15
0
0
8
36
0
8
0
8
36
8
0
8
0
8
% D
% Glu:
0
8
8
0
0
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
15
58
0
0
8
0
15
8
0
0
8
0
8
8
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
43
0
8
0
0
% H
% Ile:
8
0
0
8
0
0
0
8
0
8
0
0
0
0
8
% I
% Lys:
0
0
8
36
8
8
0
8
65
0
0
15
36
8
15
% K
% Leu:
0
8
0
8
15
15
58
8
0
0
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
8
22
0
0
0
0
0
% N
% Pro:
0
0
22
8
0
8
0
0
15
0
8
0
0
8
58
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
15
43
22
58
0
% R
% Ser:
43
15
0
29
8
0
8
15
0
0
0
0
8
15
0
% S
% Thr:
0
0
0
0
0
8
8
50
0
8
0
8
8
8
0
% T
% Val:
8
8
58
0
8
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _