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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K7
All Species:
22.42
Human Site:
T83
Identified Species:
37.95
UniProt:
O14733
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14733
NP_660186.1
419
47485
T83
G
L
P
S
T
L
F
T
P
R
S
M
E
S
I
Chimpanzee
Pan troglodytes
XP_001146898
522
57631
T179
G
L
P
S
T
L
F
T
P
R
S
M
E
S
I
Rhesus Macaque
Macaca mulatta
XP_001098659
367
41194
S48
P
I
I
V
I
T
L
S
P
A
P
A
P
S
Q
Dog
Lupus familis
XP_868281
419
47531
T83
G
L
P
S
T
L
F
T
P
R
S
M
E
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE90
535
59294
T99
G
L
P
S
T
L
F
T
P
R
S
M
E
S
I
Rat
Rattus norvegicus
Q4KSH7
419
47517
T83
G
L
P
S
T
L
F
T
P
R
S
M
E
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q07192
446
50082
N112
G
A
K
A
L
S
T
N
E
Q
A
T
K
N
R
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
L42
K
L
P
K
E
L
K
L
P
K
E
V
F
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23977
1178
125089
T160
P
V
I
L
P
L
P
T
P
P
H
P
P
V
S
Honey Bee
Apis mellifera
XP_396834
762
86143
S74
K
Q
D
S
E
F
E
S
K
L
Q
E
I
M
K
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
S44
P
E
E
S
V
L
R
S
L
S
T
G
T
L
K
Sea Urchin
Strong. purpuratus
XP_795810
281
31449
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A06
354
39192
L35
G
T
F
K
D
G
D
L
R
V
N
K
D
G
I
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
K323
G
L
F
A
N
F
S
K
Y
V
D
I
K
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
83.5
99
N.A.
77.1
99
N.A.
N.A.
N.A.
40.3
39.3
N.A.
22.4
35.2
34.8
43.6
Protein Similarity:
100
78.1
83.7
99.5
N.A.
77.5
99.5
N.A.
N.A.
N.A.
54.4
56.7
N.A.
27.5
43.3
52
54.4
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
N.A.
6.6
26.6
N.A.
20
6.6
13.3
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
N.A.
N.A.
40
40
N.A.
26.6
13.3
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
15
0
0
0
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
0
8
0
8
0
0
% D
% Glu:
0
8
8
0
15
0
8
0
8
0
8
8
36
8
0
% E
% Phe:
0
0
15
0
0
15
36
0
0
0
0
0
8
0
0
% F
% Gly:
58
0
0
0
0
8
0
0
0
0
0
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
15
0
8
0
0
0
0
0
0
8
8
0
43
% I
% Lys:
15
0
8
15
0
0
8
8
8
8
0
8
15
0
22
% K
% Leu:
0
50
0
8
8
58
8
15
8
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
36
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
8
0
0
8
0
% N
% Pro:
22
0
43
0
8
0
8
0
58
8
8
8
15
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
8
0
8
36
0
0
0
0
8
% R
% Ser:
0
0
0
50
0
8
8
22
0
8
36
0
0
50
8
% S
% Thr:
0
8
0
0
36
8
8
43
0
0
8
8
8
0
0
% T
% Val:
0
8
0
8
8
0
0
0
0
15
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _