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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT8
All Species:
26.36
Human Site:
Y214
Identified Species:
64.44
UniProt:
O14734
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14734
NP_005460.2
319
35914
Y214
F
W
V
R
A
R
G
Y
I
G
E
G
D
M
K
Chimpanzee
Pan troglodytes
XP_001158053
319
35882
Y214
F
W
V
R
A
R
G
Y
I
G
E
G
D
M
K
Rhesus Macaque
Macaca mulatta
XP_001108571
292
33173
P189
E
V
P
I
E
I
K
P
I
N
P
S
P
L
S
Dog
Lupus familis
XP_534440
317
35817
Y212
F
W
V
R
A
R
G
Y
I
G
E
G
D
M
K
Cat
Felis silvestris
Mouse
Mus musculus
P58137
320
35809
Y215
F
W
V
R
A
R
G
Y
I
G
E
G
D
I
K
Rat
Rattus norvegicus
Q8VHK0
320
35985
Y215
F
W
V
R
A
R
G
Y
I
G
E
G
D
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417475
322
36131
Y218
F
W
V
R
A
R
G
Y
I
G
E
T
D
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001006072
320
35996
Y217
I
W
V
R
A
R
G
Y
I
G
P
G
D
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508159
327
36962
E226
M
I
W
I
R
A
R
E
N
L
G
D
D
H
R
Sea Urchin
Strong. purpuratus
XP_794104
315
35947
K212
L
M
I
W
V
K
V
K
G
D
I
G
E
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
87.1
88.4
N.A.
84.6
85.6
N.A.
N.A.
73.9
N.A.
66.8
N.A.
N.A.
N.A.
39.4
48.9
Protein Similarity:
100
100
89
92.4
N.A.
92.1
92.1
N.A.
N.A.
84.7
N.A.
76.8
N.A.
N.A.
N.A.
56.5
67
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
10
80
0
0
% D
% Glu:
10
0
0
0
10
0
0
10
0
0
60
0
10
0
0
% E
% Phe:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
70
0
10
70
10
70
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
10
10
20
0
10
0
0
80
0
10
0
0
20
0
% I
% Lys:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
70
% K
% Leu:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
0
0
50
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% N
% Pro:
0
0
10
0
0
0
0
10
0
0
20
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
70
10
70
10
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% T
% Val:
0
10
70
0
10
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
70
10
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _