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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDIPT All Species: 21.82
Human Site: T179 Identified Species: 36.92
UniProt: O14735 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14735 NP_006310.1 213 23539 T179 F R M G L W V T A P I A L L K
Chimpanzee Pan troglodytes XP_001145072 185 20227 I161 I A L L K S L I S V I H L I T
Rhesus Macaque Macaca mulatta XP_001105279 213 23619 T179 F R M G L W V T A P I A L L K
Dog Lupus familis XP_849200 213 23430 T179 F R V G L W I T A P I A A L K
Cat Felis silvestris
Mouse Mus musculus Q8VDP6 213 23580 T179 F R M G L W V T A P I A L L K
Rat Rattus norvegicus P70500 213 23594 T179 F R M G L W I T A P I A L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517127 322 34929 W286 G L F R V G V W L S A P I T F
Chicken Gallus gallus
Frog Xenopus laevis NP_001084752 218 24243 L179 G A V G L F R L I V W L C C P
Zebra Danio Brachydanio rerio NP_996971 213 23960 C179 L G V C G V V C L L K S G I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573055 224 25486 A182 A F L T G P F A V L K A L I S
Honey Bee Apis mellifera XP_394882 217 24860 S180 F R L V M Y L S A P I A F I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798034 218 24532 L178 L F R M I F Y L S T P I A I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GUK6 225 25562 P183 K S L M Q I S P L S L L L A L
Baker's Yeast Sacchar. cerevisiae P06197 220 24805 V188 I I S F P G Y V F K Q T A N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.8 99 94.3 N.A. 96.2 95.3 N.A. 57.1 N.A. 74.3 69.9 N.A. 49.5 51.1 N.A. 57.3
Protein Similarity: 100 86.8 99.5 98.1 N.A. 98.5 98.5 N.A. 63.3 N.A. 88.9 81.6 N.A. 65.6 71.4 N.A. 76.6
P-Site Identity: 100 13.3 100 80 N.A. 100 93.3 N.A. 6.6 N.A. 13.3 6.6 N.A. 13.3 46.6 N.A. 0
P-Site Similarity: 100 40 100 93.3 N.A. 100 100 N.A. 20 N.A. 26.6 26.6 N.A. 26.6 86.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 35.1 37.7 N.A.
Protein Similarity: N.A. N.A. N.A. 56 54.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 0 0 0 0 8 43 0 8 50 22 8 0 % A
% Cys: 0 0 0 8 0 0 0 8 0 0 0 0 8 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 43 15 8 8 0 15 8 0 8 0 0 0 8 0 8 % F
% Gly: 15 8 0 43 15 15 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 15 8 0 0 8 8 15 8 8 0 50 8 8 36 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 8 15 0 0 0 43 % K
% Leu: 15 8 29 8 43 0 15 15 22 15 8 15 50 36 8 % L
% Met: 0 0 29 15 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 8 8 0 8 0 43 8 8 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 43 8 8 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 8 0 0 8 8 8 15 15 0 8 0 0 15 % S
% Thr: 0 0 0 8 0 0 0 36 0 8 0 8 0 8 8 % T
% Val: 0 0 22 8 8 8 36 8 8 15 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 36 0 8 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 15 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _