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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDIPT All Species: 43.64
Human Site: Y134 Identified Species: 73.85
UniProt: O14735 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14735 NP_006310.1 213 23539 Y134 G N P V L R I Y Y T S R P A L
Chimpanzee Pan troglodytes XP_001145072 185 20227 L116 S R P A L F T L C A G N E L F
Rhesus Macaque Macaca mulatta XP_001105279 213 23619 Y134 G N P V L R I Y Y T S R P A L
Dog Lupus familis XP_849200 213 23430 Y134 G N P V L R I Y Y T S R P A L
Cat Felis silvestris
Mouse Mus musculus Q8VDP6 213 23580 Y134 G N P V L R I Y Y T S R P A L
Rat Rattus norvegicus P70500 213 23594 Y134 G N P V L R I Y Y T S R P A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517127 322 34929 Y241 G N P V L R L Y Y T S R P V L
Chicken Gallus gallus
Frog Xenopus laevis NP_001084752 218 24243 Y134 G N P V L R L Y Y T S R P V L
Zebra Danio Brachydanio rerio NP_996971 213 23960 Y134 G N P I L R L Y Y T S R P V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573055 224 25486 K137 I M R L Y Y Q K D I L T F M C
Honey Bee Apis mellifera XP_394882 217 24860 Y135 E N P I M R L Y Y T N R K V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798034 218 24532 Y133 E N P I L A V Y Y T S R P V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GUK6 225 25562 Y138 T S W L F R L Y Y G N R M F M
Baker's Yeast Sacchar. cerevisiae P06197 220 24805 Y143 E S R L L H L Y Y T R R D V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.8 99 94.3 N.A. 96.2 95.3 N.A. 57.1 N.A. 74.3 69.9 N.A. 49.5 51.1 N.A. 57.3
Protein Similarity: 100 86.8 99.5 98.1 N.A. 98.5 98.5 N.A. 63.3 N.A. 88.9 81.6 N.A. 65.6 71.4 N.A. 76.6
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 86.6 N.A. 86.6 80 N.A. 0 53.3 N.A. 66.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 35.1 37.7 N.A.
Protein Similarity: N.A. N.A. N.A. 56 54.5 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 0 8 0 0 0 36 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % D
% Glu: 22 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 8 8 8 % F
% Gly: 58 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 22 0 0 36 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 22 79 0 43 8 0 0 8 0 0 8 79 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 0 8 8 8 % M
% Asn: 0 72 0 0 0 0 0 0 0 0 15 8 0 0 0 % N
% Pro: 0 0 79 0 0 0 0 0 0 0 0 0 65 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 15 0 0 72 0 0 0 0 8 86 0 0 0 % R
% Ser: 8 15 0 0 0 0 0 0 0 0 65 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 8 0 0 79 0 8 0 0 0 % T
% Val: 0 0 0 50 0 0 8 0 0 0 0 0 0 43 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 86 86 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _