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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 11.52
Human Site: S1045 Identified Species: 21.11
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S1045 D T A S L C Y S I L K A K N A
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S1048 D T A S L C Y S I L K A K N A
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S1045 D T A S L C Y S I L K A K N A
Dog Lupus familis XP_851664 1092 121456 H1003 L L Q A Y R F H A C V L Q L P
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 C1035 I I S S Q A S C C Y A I L K V
Rat Rattus norvegicus Q673L6 1125 126915 A1038 N L A S C C Y A I L K V K N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 F1259 D T A S C C Y F I L K A K N P
Frog Xenopus laevis NP_001079102 1191 137998 T1104 D M A P C F Y T T F K A K N K
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 K1012 R M T R V T N K L L T H I N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 A1225 S C V R I F H A C T V S K L R
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 L1103 T F R Y M H S L V A K R M H E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 R1037 I S V R Y M F R L I N R R V R
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 F798 S E C Y K S A F K D L S I N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 0 N.A. 6.6 60 N.A. N.A. 80 46.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 20 N.A. 13.3 73.3 N.A. N.A. 80 53.3 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 26.6 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 47 8 0 8 8 16 8 8 8 39 0 0 24 % A
% Cys: 0 8 8 0 24 39 0 8 16 8 0 0 0 0 0 % C
% Asp: 39 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 8 0 0 0 16 16 16 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 8 8 0 0 0 8 0 8 0 % H
% Ile: 16 8 0 0 8 0 0 0 39 8 0 8 16 0 0 % I
% Lys: 0 0 0 0 8 0 0 8 8 0 54 0 54 8 16 % K
% Leu: 8 16 0 0 24 0 0 8 16 47 8 8 8 16 0 % L
% Met: 0 16 0 0 8 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 0 0 8 0 0 62 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 24 % P
% Gln: 0 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 8 24 0 8 0 8 0 0 0 16 8 0 16 % R
% Ser: 16 8 8 47 0 8 16 24 0 0 0 16 0 0 0 % S
% Thr: 8 31 8 0 0 8 0 8 8 8 8 0 0 0 0 % T
% Val: 0 0 16 0 8 0 0 0 8 0 16 8 0 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 16 16 0 47 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _