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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 13.03
Human Site: S1104 Identified Species: 23.89
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S1104 R T A Q T Q L S R K L P G T T
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S1107 R T A Q T Q L S R K L P G T T
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S1104 R T A Q T Q L S R K L P G T T
Dog Lupus familis XP_851664 1092 121456 R1061 L F P S E A A R W L C L H A F
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 C1094 R T A Q K L L C R K L P E A T
Rat Rattus norvegicus Q673L6 1125 126915 C1097 R T A Q K Q L C R K L P E A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 F1318 K V Y K M H L F G K I P R D T
Frog Xenopus laevis NP_001079102 1191 137998 S1163 Q N C K M Q L S R R L S Q D T
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 Q1071 H K R K R A L Q R E L C G I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 A1284 R K H R Q K A A L K M G K A M
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 C1161 L R E E I G R C G H L D R H N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 H1096 L K S A L S K H S L S Q Q L S
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 S856 E S L S S N T S K F K D N I I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 0 N.A. 66.6 73.3 N.A. N.A. 26.6 40 33.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 0 N.A. 66.6 73.3 N.A. N.A. 46.6 60 46.6 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 39 8 0 16 16 8 0 0 0 0 0 31 0 % A
% Cys: 0 0 8 0 0 0 0 24 0 0 8 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 16 0 16 0 % D
% Glu: 8 0 8 8 8 0 0 0 0 8 0 0 16 0 0 % E
% Phe: 0 8 0 0 0 0 0 8 0 8 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 8 0 0 16 0 0 8 31 0 0 % G
% His: 8 0 8 0 0 8 0 8 0 8 0 0 8 8 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 8 0 0 16 8 % I
% Lys: 8 24 0 24 16 8 8 0 8 54 8 0 8 0 0 % K
% Leu: 24 0 8 0 8 8 62 0 8 16 62 8 0 8 0 % L
% Met: 0 0 0 0 16 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 47 0 0 0 % P
% Gln: 8 0 0 39 8 39 0 8 0 0 0 8 16 0 0 % Q
% Arg: 47 8 8 8 8 0 8 8 54 8 0 0 16 0 0 % R
% Ser: 0 8 8 16 8 8 0 39 8 0 8 8 0 0 8 % S
% Thr: 0 39 0 0 24 0 8 0 0 0 0 0 0 24 62 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _