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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 11.52
Human Site: S191 Identified Species: 21.11
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S191 A R P P P H A S G P R R R L G
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S191 A R P P P H A S G P R R R L G
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S191 G R P A A H A S G T R R G L G
Dog Lupus familis XP_851664 1092 121456 S183 Y D L C A P A S L P L P A P G
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 S191 I W P S V S A S Y R P T R P V
Rat Rattus norvegicus Q673L6 1125 126915 G191 T W S S V P A G Y R P T R P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 R210 G P S P G F V R R R Y S R F K
Frog Xenopus laevis NP_001079102 1191 137998 F193 F L F Q S Q S F T Q S N V L L
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 N189 W S G F F L S N S D N E R I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 K309 M A P G K Y D K T L Q R T C R
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 Q206 F A S A A K N Q Q P Q S T K G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 S175 G K K H Q Q V S G P P L C I K
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 N19 L D I D L Q T N S T Y K E N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 66.6 26.6 N.A. 26.6 13.3 N.A. N.A. 13.3 6.6 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 66.6 26.6 N.A. 26.6 13.3 N.A. N.A. 13.3 13.3 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 13.3 N.A. 20 0 N.A.
P-Site Similarity: N.A. 20 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 0 16 24 0 47 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 16 0 8 0 0 8 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % E
% Phe: 16 0 8 8 8 8 0 8 0 0 0 0 0 8 0 % F
% Gly: 24 0 8 8 8 0 0 8 31 0 0 0 8 0 39 % G
% His: 0 0 0 8 0 24 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 0 0 0 0 16 0 % I
% Lys: 0 8 8 0 8 8 0 8 0 0 0 8 0 8 16 % K
% Leu: 8 8 8 0 8 8 0 0 8 8 8 8 0 31 16 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 16 0 0 8 8 0 8 0 % N
% Pro: 0 8 39 24 16 16 0 0 0 39 24 8 0 24 0 % P
% Gln: 0 0 0 8 8 24 0 8 8 8 16 0 0 0 0 % Q
% Arg: 0 24 0 0 0 0 0 8 8 24 24 31 47 0 8 % R
% Ser: 0 8 24 16 8 8 16 47 16 0 8 16 0 0 8 % S
% Thr: 8 0 0 0 0 0 8 0 16 16 0 16 16 0 0 % T
% Val: 0 0 0 0 16 0 16 0 0 0 0 0 8 0 16 % V
% Trp: 8 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 16 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _